LDL R Blocking Peptide - (Dry Ice)
货号：
NBP1-06709PEP 基本售价：
1219.4 元 规格：
0.1 ml
产品信息
概述| 货号 | NBP1-06709PEP |
| 反应种属 | HuSpecies Glossary |
| 应用 | WB |
性能| 供应商 | Novus |
| 免疫原 | Synthetic peptide made to an internal portion of the human protein (within residues 500-550). [Swiss-Prot# P01130] |
| 背景 | The low density lipoprotein (LDL) receptor system coordinates the metabolism of cholesterol, an essential component of the plasma membrane of all mammalian cells. Study of this system has led to an enhanced understanding of the cellular basis of cholesterol homeostasis. It has also brought into focus an important mechanism of metabolic regulation--the process of receptor-mediated endocytosis (1). Data suggest that the juxtamembranous region of the cytoplasmic domain participates in protein:protein interactions that allow the low density lipoprotein receptor to cluster in coated pits (2). It has been shown that the family of LDL receptors may serve as viral receptors. Endocytosis of the Flaviviridae viruses, hepatitis C virus, GB virus C/hepatitis G virus, and bovine viral diarrheal virus (BVDV) was shown to be mediated by LDL receptors on cultured cells (3). |
| 运输条件 | Dry Ice |
| 存放说明 | Store at -80C. Avoid freeze-thaw cycles. |
| 存储溶液 | PBS, 30% glycerol |
| 浓度 | 1.0 mg/ml |
| 纯度 | Immunogen affinity purified |
