ATG16L1 Blocking Peptide - (Dry Ice)
货号:
NB110-82384PEP 基本售价:
1219.4 元 规格:
0.1 ml
产品信息
概述货号 | NB110-82384PEP |
反应种属 | MuSpecies Glossary |
目标/特异性 | This peptide is specific for NB110-82384 only. |
性能供应商 | Novus |
背景 | Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). The APG12-APG5-APG16L complex is essential for the elongation of autophagic isolation membranes. This complex initially associates in uniform distribution with small vesicle membranes. During membrane elongation, the complex partitions, with a great concentration building on the outer side of the isolation membrane. Upon completion of the formation of the autophagosome, the APG12-APG5-APG16L dissociates from the membrane. |
运输条件 | Dry Ice |
存放说明 | Store at -80C. Avoid freeze-thaw cycles. |
存储溶液 | Peptide dissolved in dH2O. Contains no BSA. |
浓度 | 1.0 mg/ml |