| 货号 | 3705-KS-010 |
| 别名 | EC 2.7.11; EC 2.7.11.1; MAP kinase-activated protein kinase 2; MAPK-activated protein kinase 2; MAPKAP kinase 2; MAPKAPK-2; mitogen-activated protein kinase-activated protein kinase 2; MK2; Rps6kc1 | 全称 | Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 |
| 反应种属 | Human |
| 来源 | Spodoptera frugiperda,Sf 9 (baculovirus)-derived Accession # NM_032960 |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 9261 (Human); 17164 (Mouse); 289014 (Rat) |
| 生物活性 | The activity of MAPKAPK2 is typically 233-315 nmol/min/mg using a synthetic peptide substrate (RRLNRQLSVA-amide) (see Activity Assay Protocol). |
| 背景 | MAPKAPK2 (MAPKAP kinase 2) is a Ser/Thr protein kinase which is regulated via direct phosphorylation by p38 MAP kinase (1). In conjunction with p38 MAP kinase, MAPKAPK2 is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation, and cell proliferation. Heat shock protein 27 (HSP27) has been shown to be one of the substrates of MAPKAPK2 in vivo. |
| Accession # | NM_032960 |
| 运输条件 | Dry Ice |
| N-terminal Sequence Analysis | Using an N-terminal GST tag |
| SDS-PAGE | 68 kDa |
| 存放说明 | -80℃ |
| 纯度 | >70%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain at 5 μg per lane |
| 参考文献 |
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The approximate molecular weight is 68 kDa and the average purity is 90%. |
