Recombinant Human Active RSK1 Protein, CF (10 UG)
货号:
992-KS-010 基本售价:
4858.1 元 规格:
10 ug
产品信息
概述货号 | 992-KS-010 |
别名 | 90kD, polypeptide 1); EC 2.7.11; EC 2.7.11.1,90 kDa ribosomal protein S6 kinase 1; HU-1; MAP kinase-activated protein kinase 1a; MAPK-activated protein kinase 1a; MAPKAP kinase 1a; MAPKAPK-1a; MAPKAPL1A; p90RSK1; p90S6K; ribosomal protein S6 kinase alpha 1; ribosomal protein S6 kinase alpha-1; ribosomal protein S6 kinase, 90kD, polypeptide 1; ribosomal protein S6 kinase, 90kDa, polypeptide 1; Ribosomal S6 kinase 1; RPS6KA1; RSK; RSK-1; RSK1p90-RSK 1; S6K-alpha 1; S6K-alpha-1 |
全称 | Ribosomal Protein S6 Kinase I | 反应种属 | Human |
来源 | Spodoptera frugiperda,Sf 9 (baculovirus)-derived |
产品组分 | |
性能供应商 | R&D Systems |
Entrez Gene IDs | 6195 (Human); 20111 (Mouse); 81771 (Rat) |
生物活性 | The activity of RSK1 is typically 159-215 nmol/min/mg using a synthetic peptide substrate (see Activity Assay Protocol). |
背景 | RSK1 is a member of the RSK (ribosomal S6 kinase) family that consists of growth factor-regulated serine/threonine kinases. RSK1 contains two non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signaling pathway. RSK1 encodes a predicted 735 amino acid protein containing 2 distinct consensus ATP-binding site sequences. RSK1 transcript is present in lymphocytes, skeletal muscle, liver, and adipose tissue (1). RSKs are implicated in the activation of the mitogen-activated kinase (MAPK) cascade and the stimulation of cell proliferation and differentiation (2). |
Accession # | NM_002953 |
运输条件 | Dry Ice |
N-terminal Sequence Analysis | Using an N terminal GST Tag
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SDS-PAGE | The approximate molecular weight is 108 kDa |
存放说明 | -80℃ |
纯度 | >70%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain at 5 μg per lane. |
参考文献 | - Moller, D.E. et al. (1994) Am. J. Physiol. 266:C351.
- Gross, S.D. et al. (1999) Science 286:1365.
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参考图片The approximate molecular weight is 108 kDa and the average purity is 90%. |