| 货号 | 4596-KS-010 |
| 别名 | cAMP-dependent protein kinase catalytic beta subunit isoform 4ab; cAMP-dependent protein kinase catalytic subunit beta; cAPKbeta; DKFZp781I2452; EC 2.7.11; EC 2.7.11.11; MGC41879; MGC9320; PKA C-beta; PKACb; PRKACB; protein kinase A catalytic subunit beta; protein kinase, cAMP-dependent, catalytic, beta | 全称 | cAMP-dependent Protein Kinase Catalytic Subunit beta |
| 反应种属 | Human |
| 来源 | Spodoptera frugiperda,Sf 9 (baculovirus)-derived Accession # NM_002731 |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 5567 (Human); 18749 (Mouse); 293508 (Rat) |
| 应用文献 | |
| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Cross-talk between PKA-Cbeta and p65 mediates synergistic induction of PDE4B by roflumilast and NTHi. | |
| 生物活性 | The activity of PKA C beta is typically 423-573 nmol/min/mg using a synthetic peptide substrate (see Activity Assay Protocol). |
| 背景 | The catalytic subunit C-beta of PKA (PKA C beta ) is a member of the Ser/Thr protein kinase family (the PKA catalytic subunit consists of three gene products: C alpha, C beta, and C gamma ) and has been assigned to human chromosome region 1p36.1 (1). PKA C beta is derived from a gene distinct from C alpha and shows tissue-specific expression. At the amino acid level C alpha and C beta showed 93% homology. |
| Accession # | NM_002731 |
| 运输条件 | Dry Ice |
| N-terminal Sequence Analysis | Using an N-terminal GST tag |
| SDS-PAGE | 65 kDa |
| 存放说明 | -80℃ |
| 纯度 | >70%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain at 5 μg per lane |
| 参考文献 |
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The approximate molecular weight is 65 kDa and the average purity is 90%. |
