Recombinant Human Active PIM1 Protein, CF (10 UG)
货号：
4588-KS-010 基本售价：
4858.1 元 规格：
10 ug
产品信息
概述| 货号 | 4588-KS-010 |
| 别名 | EC 2.7.11.1; Oncogene PIM1; PIM; pim-1 kinase 44 kDa isoform; pim-1 oncogene (proviral integration site 1); pim-1 oncogene; proto-oncogene serine/threonine-protein kinase pim-1 |
全称 | Proviral Integration Site 1 | | 反应种属 | Human |
| 来源 | Spodoptera frugiperda,Sf 9 (baculovirus)-derived Accession # NM_002648 |
| 产品组分 | |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 5292 (Human); 18712 (Mouse); 24649 (Rat) |
| 生物活性 | The activity of PIM1 is typically 269-363 nmol/min/mg using a synthetic peptide substrate (see Activity Assay Protocol). |
| 背景 | PIM1 is a proto-oncogene that belongs to a family of Ser/Thr protein kinases that are highly conserved through evolution in multicellular organisms. Originally identified from Moloney murine leukemia virus induced T cell lymphomas in mice, PIM1 is involved in the control of cytokine-mediated cell proliferation, differentiation, and survival of lymphoid and myeloid cells as well as others (1). Expression of PIM1 can be stimulated by a variety of growth factors and is regulated at four different levels: transcriptional, post-transcriptional, translational, and post-translational (2). Expression of PIM1 is mediated through activation of the JAK/STAT pathway. |
| Accession # | NM_002648 |
| 运输条件 | Dry Ice |
N-terminal
Sequence Analysis | Using an N-terminal GST tag |
| SDS-PAGE | 62 kDa |
| 存放说明 | -80℃ |
| 纯度 | >70%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain at 5 μg per lane |
| 参考文献 | - Meeker, T.C. et al. (1987) J. Cell. Biochem. 35:105.
- Friedmann, M. et al. (1992) Arch. Biochem. Biophys. 298:594.
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参考图片The approximate molecular weight is 62 kDa and the average purity is 90%. |
