| 货号 | 3206-KS-010 |
| 别名 | Lyn B | 全称 | V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog |
| 反应种属 | Human |
| 来源 | Spodoptera frugiperda,Sf 9 (baculovirus)-derived Accession # BC059394 |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 4067 (Human); 17096 (Mouse); 81515 (Rat) |
| 生物活性 | The activity of Lyn B is typically 205-277 nmol/min/mg using a synthetic peptide substrate (see Activity Assay Protocol). |
| 背景 | Lyn B is a tyrosine kinase that is similar to mouse T-lymphocyte-specific tyrosine kinase p56lck, v-yes, v-fgr, and v src and is expressed in a variety of tissues (1). Lyn B is expressed preferentially in B cells and can be co-immunoprecipitated with IgM suggesting that Lyn B is physically associated with membrane-bound IgM, and participates in antigen-mediated signal transduction (2). Cross-linking of membrane-bound IgM with antibody induces a rapid increase in activities of Lyn B and Lyn-associated phosphatidylinositol 3-kinase. |
| Accession # | BC059394 |
| 运输条件 | Dry Ice |
| N-terminal Sequence Analysis | Using an N-terminal GST tag |
| SDS-PAGE | 85 kDa |
| 存放说明 | -80℃ |
| 纯度 | >70%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain at 5 μg per lane |
| 参考文献 |
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The approximate molecular weight is 85 kDa and the average purity is 90%. |
