Recombinant Human Active Blk Protein, CF (10 UG)
货号：
2679-KS-010 基本售价：
4858.1 元 规格：
10 ug
产品信息
概述| 货号 | 2679-KS-010 |
| 别名 | B lymphocyte kinase; B lymphoid tyrosine kinase; BLK nonreceptor tyrosine kinase; EC 2.7.10.2; MGC10442; MODY11; p55-Blk; tyrosine-protein kinase Blk |
全称 | B Lymphoid Tyrosine Kinase | | 反应种属 | Human |
| 来源 | Spodoptera frugiperda,Sf 9 (baculovirus)-derived Accession # BC_007371 |
| 产品组分 | |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 640 (Human); 12124 (Mouse); 364403 (Rat) |
| 生物活性 | The activity of Blk is typically 95-129 nmol/min/mg using a poly (Glu:Tyr, 4:1) synthetic peptide substrate (see Activity Assay Protocol). |
| 背景 | Blk, also known as B lymphoid kinase, is a 55 kDa tyrosine kinase with SH3, SH2, and catalytic domains that contain consensus sequences of the Src protein tyrosine kinase family. Blk is expressed specifically in the B cell lineage and plays a role in the signal transduction pathway that is restricted to B lymphoid cells (1). Stimulation of resting B-lymphocytes with antibodies to surface immunoglobulin (sIgD or sIgM) induces activation of Blk (2). |
| Accession # | BC_007371 |
| 运输条件 | Dry Ice |
N-terminal
Sequence Analysis | Using an N terminal GST tag |
| 预期分子量 | 84 kDa |
| 存放说明 | -80℃ |
| 纯度 | >70%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain at 5 μg per lane |
| 参考文献 | - Dymecki, S.M. et al. (1990) Science 247:332.
- Burkhardt, A.L. et al. (1991) Proc. Natl. Acad. Sci. USA 88:7410.
|
参考图片The approximate molecular weight is 84 kDa and the average purity is 90%. |
