概述货号 | SP-305-020 |
别名 | SUMO |
全称 | Small Ubiquitin-like Modifiers |
性能供应商 | R&D Systems |
溶解方法 | Reconstitution default not known |
背景 | This biotinylated peptide serves as a negative control and contains a scrambled version of the consensus motif sequence (SP-300). It will not be conjugated to SUMO1, SUMO2 or SUMO3 proteins in the presence of the E1 activating (SAE1/SAE2) and Ubc9 conjugating enzymes. The biotin group allows for sensitive and convenient detection using avidin-linked reagents. SUMO modification of proteins occurs on lysine residues generally found within a short consensus sequence containing the psi ΚXE motif. This motif consists of psi which represents a large hydrophobic amino acid (isoleucine, leucine or valine), K is the lysine that becomes modified, X is any residue and E is glutamic acid. The glutamic acid is the most highly conserved position other than the lysine.
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运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 | - Negative Regulators of the Jak/STAT Pathway
- Ubiquitin-like Modifiers (UBLs) and Regulators
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