Rat CD252 Ligand Pure ATM-2 500ug
货号：
559957 基本售价：
9858.0 元 规格：
500ug
产品信息
概述| 货号 | 559957 |
| 描述 | The ATM-2 antibody reacts with rat CD252 (OX-40 Ligand, OX-40L), a member of the TNF Ligand superfamily. Although there is controversy regarding mouse OX-40L expression, OX-40L has been shown to be expressed on human dendritic cells and mouse activated B lymphocytes. Rat OX-40L interacts with OX-40 Antigen (CD134) found predominantly on activated T cells. The OX-40L-OX-40 interaction is reciprocally costimulatory in that both T cells and B cells are activated in cross-linking. Rat OX-40L mRNA has been detected in various HTLV-I-transformed T-cell lines: F344-S1, WKA-S1, and ACI-S1. In addition, total rat spleen cells activated with 5 ng/ml PMA and 0.5 µg/ml ionomycin for two days showed OX-40L expression, as determined by flow cytometric analysis, with the ATM-2 mAb. As observed in the mouse and human systems, rat OX-40L also costimulates IL-2 production and proliferation of anti- D3-activated rat T cells. The ATM-2 mAb blocks the costimulatory activity of OX-40L on rat T- cell proliferation. |
| 别名 | Tnfsf4; OX40 ligand; OX40L; TXGP1; Txgp1l; gp34; Ath-1; Ath1; CD134L |
| 同种亚型 | IgG1,κ |
| 反应种属 | Rat (QC Testing) |
| 来源宿主 | Mouse |
| 使用方法 | FC |
性能| 供应商 | BD Pharmingen |
| 免疫原 | ACI-S1 rat T-cell lymphoma cell line |
| 存放说明 | Store undiluted at 4°C.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
|
| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.5 mg/ml |
