| 货号 | FAB7438G |
| 别名 | B2M; beta chain of MHC class I molecules; beta-2-microglobin; beta-2-microglobulin |
| 反应种属 | Rat |
| 应用 | Flow Cytometry |
| 目标/特异性 | Detects rat beta 2-Microglobulin in direct ELISAs.In direct ELISAs, no cross-reactivitywith recombinant rat alpha 2-Macroglobulin is observed. |
| 使用方法 | Flow Cytometry: 5 µL/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 567 (Human); 12010 (Mouse); 24223 (Rat) |
| 纯化方式 | IgM-specific Affinity-purified from hybridoma culture supernatant |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant rat beta 2-Microglobulin Ile21-Met119 Accession # P07151 |
| 生物活性 | Rat |
| 标记 | Alexa Fluor 488 |
| 背景 | beta2-Microglobulin ( beta 2M) is a ubiquitous, 12 kDa, secreted, non-glycosylated protein required for cell surface expression and non-covalent assembly of MHC Class I molecules and CD1 cell surface glycoproteins. Mature rat beta 2M is a 99 amino acid (aa) peptide containing one C1-type lg-like domain (aa 22-116). In humans, beta 2M is known to dissociate from the MHC complex and circulate as full-length and N-terminal-truncated peptides of 93, 91, and 90 amino acids. Mature rat beta 2M is 86% and 75% identical to the corresponding mouse and human protein sequences, respectively. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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Detection of beta 2‑Microglobulin in Rat Splenocytes by Flow Cytometry. Rat splenocytes were stained with mouse anti-rat CD3 phycoerythrin‑conjugated monoclonal antibody and either (A) Mouse Anti-Rat beta 2‑Microglobulin Alexa Fluor® 488‑conjugated Monoclonal Antibody (Catalog # FAB7438G) or (B) Normal Mouse IgM Alexa Fluor 488 Control (Catalog # IC015G). View our protocol for Staining Membrane-associated Proteins. |
