Rat CD31 BB515 TLD-3A12 50ug
货号：
565408 基本售价：
4750.0 元 规格：
50ug
产品信息
概述| 货号 | 565408 |
| 描述 | The TLD-3A12 antibody reacts with CD31, also known as PECAM-1 (platelet endothelial cell adhesion molecule). CD31 is a ~130 kDa integral membrane glycoprotein, a member of the immunoglobulin super family, that mediates homophilic and heterophilic cell-cell adhesion. CD31 is expressed on endothelial cells, platelets, and subsets of leukocytes. CD31-mediated endothelial cell-cell interactions are involved in angiogenesis in the mouse and rat. In addition, PECAM-1 has been demonstrated to play an important role in extravasation of leukocytes in vivo, but in vivo treatment with TLD-3A12 mAb had no discernable effect upon the inflammatory infiltrate in experimental allergic encephalomyelitis. The TLD-3A12 mAb partially blocks the proliferative response of antigen-specific CD4+ T cells to antigen-presenting cells and relevant antigen. The mouse anti-rat CD31 antibody cross-reacts with pig endothelial cells and platelets, as determined by immunohistochemical staining of acetone-fixed frozen sections and immunofluorescent staining with flow cytometric analysis. A suspension of Lewis rat microglial cells were used as the source of the immunogen. |
| 别名 | PECAM-1 |
| 同种亚型 | Mouse BALB/c IgG1, κ |
| 反应种属 | Rat (QC Testing) Pig (Tested in Development) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Lewis Rat Microglia |
| 标记 | BB515 |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon™ BB515 under optimum conditions and unconjugated antibody was removed.
|
| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.2 mg/ml |
