货号 | FAB8368P-100 |
别名 | C-C chemokine receptor type 2; C-C CKR-2; CC-CKR-2CKR2B; CCR2; CCR-2; CCR2A; CCR2B; CD192 antigen; CD192; chemokine (C-C motif) receptor 2; CKR2; CKR2A; CMKBR2MGC111760; FLJ78302; MCP-1 receptor; MCP-1-RMGC103828; MGC168006; Monocyte chemoattractant protein 1 receptor; monocyte chemotactic protein 1 receptor |
反应种属 | Rat |
应用 | Flow Cytometry(10 µL/106cells) |
目标/特异性 | Stains rat CCR2 transfectants but not irrelevant transfectants in flow cytometry. |
使用方法 | Flow Cytometry: 10 µL/106cells |
来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 729230 (Human); 12772 (Mouse); 60463 (Rat) |
纯化方式 | Protein A or G purified from hybridoma culture supernatant |
免疫原 | NS0 mouse myeloma cell line transfected with rat CCR2 Accession # O55193 |
生物活性 | Rat |
标记 | Phycoerythrin |
背景 | CCR2, also known as CD192, is a 38 kDa 7TM chemokinereceptor that preferentially binds CCL2, CCL7, and CCL13. CCR2 is expressed bymultiple hematopoietic cells, endothelial cells, fibroblasts, neurons, andsmooth muscle cells. It functions as an HIV fusion co-factor and facilitates Tcell recruitment during inflammation. Two alternate splice forms (CCR2A andCCR2B) differ only by the addition of 14 amino acids to the intracellularcarboxyl terminal. Rat CCR2 shares 95% aa sequence identity with mouse CCR2. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
|
Detection of CCR2 in HEK293 Human Cell Line Transfected with Rat CCR2 and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with rat CCR2 and eGFP was stained with either (A) Mouse Anti-Rat CCR2 PE‑conjugated Monoclonal Antibody (Catalog # FAB8368P) or (B) Mouse IgG2B Phycoerythrin Isotype Control (Catalog # IC0041P). View our protocol for Staining Membrane-associated Proteins. |