CD252 funct. grade pure, rat
货号：
130-104-212 基本售价：
询价 规格：
EA
产品信息
概述| 货号 | 130-104-212 |
| 描述 | Clone ATM-2 recognizes the rat CD252 antigen, a member of the TNF ligand superfamily, also known as OX40 ligand (OX40L) or tumor necrosis factor ligand superfamily member 4 (Tnfsf4). CD252 is constitutively expressed by splenic dendritic cells and can be upregulated on splenic B cells via stimulation with LPS. Expression of the cognate receptor CD134 (OX40) is found predominantly on activated T cells. CD252/CD134 interaction promotes the proliferation and survival of effector T cells, modulates cytokine production, suppresses the activity of natural regulatory T cells, and inhibits the generation of inducible regulatory T cells. |
| 别名 | TNFSF4, OX40L |
| 克隆号 | ATM-2 |
| 同种亚型 | mouse IgG1κ |
