| 货号 | FAB8399A-025UG |
| 别名 | ACKR3; chemokine (C-X-C motif) receptor 7; Chemokine orphan receptor 1CMKOR1C-X-C chemokine receptor type 7; CMKOR1; CXCR7; CXC-R7; CXCR-7; G protein-coupled receptor; GPR159; GPR159G-protein coupled receptor 159; RDC-1; RDC1G-protein coupled receptor RDC1 homolog |
| 应用 | Flow Cytometry |
| 目标/特异性 | Detects HEK293 human embryonic kidney cell line transfected with rat CXCR7/RDC-1 by Flow Cytometry. Does not detect untransfected or irrelevant transfected HEK293 cells. |
| 使用方法 | Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 57007 (Human); 12778 (Mouse); 84348 (Rat) |
| 纯化方式 | Protein A or G purified from hybridoma culture supernatant |
| 免疫原 | NS0 mouse myeloma cell line transfected with rat CXCR7/RDC-1 Met1-Lys362 Accession # NP_445804 |
| 生物活性 | Rat |
| 标记 | Allophycocyanin |
| 背景 | CXCR7 (CXC Chemokine Receptor 7), also known as GPRN1, RDC-1 and Chemokine Orphan Receptor 1, is a 60 kDa member of the G-protein coupled receptor 1 family. It is expressed on multiple cell types, including neurons, T cells, NK cells, neutrophils, B cells plus angiogenic endothelial cells. CXCR7 forms both homodimers and heterodimers with CXCR4. It selectively binds I-TAC and SDF-1, and appears to involve beta -Arrestin 2 during signaling. Notably, a CXCR7:CXCR4 heterodimer shows increased responsiveness to SDF-1, and I-TAC may actually block some SDF-1-mediated migration activity. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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Detection of CXCR7/RDC‑1 in HEK293 Human Cell Line Transfected with Rat CXCR7/RDC-1 and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with either (A) rat CXCR7/RDC-1 or (B) irrelevant transfectants and eGFP was stained with Mouse Anti-Rat CXCR7/RDC‑1 APC‑conjugated Monoclonal Antibody (Catalog # FAB8399A). Quadrant markers were set based on control antibody staining (Catalog # IC003A). View our protocol for Staining Membrane-associated Proteins. |
