Rat CD11a Pure WT.1 100ug
货号：
559979 基本售价：
2323.0 元 规格：
100ug
产品信息
概述| 货号 | 559979 |
| 描述 | The WT.5 antibody reacts with the asubunit of LFA-1 (αLβ2 integrin, CD11a/CD18), a heterodimeric surface glycoprotein which is found on the majority of leukocytes, but not on peritoneal macrophages or peritoneal mast cells. LFA-1 mediates a variety of heterotypic and homotypic intercellular adhesions through interaction with ICAM-1 (CD54) and ICAM-2 (CD102). WT.1 mAb recognizes both the activated and unactivated forms of LFA-1. It inhibits the binding of LFA-1 to ICAM-1 in several in vitro assays, including binding of Concanavalin A-stimulated lymphocytes (Con A blasts) to purified ICAM-1 and Mg2+-dependent aggregation of concanavalin A-stimulated blasts. It has also been reported to inhibit leukocyte infiltration in several in vivo models of inflammation. |
| 别名 | Integrin αL chain, LFA-1 α chain |
| 同种亚型 | IgG2a,κ |
| 反应种属 | Rat (QC Testing) |
| 来源宿主 | Mouse |
| 使用方法 | FC, IHC(Fr), IP |
性能| 供应商 | BD Pharmingen |
| 免疫原 | PHA-stimulated rat splenocytes and rat thymic lymphoma FTL-43 |
| 存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.Store undiluted at 4°C.
|
| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.5 mg/ml |
