货号 | 9320T |
目标/特异性 | Each antibody in the Src Family Antibody Sampler Kit detects endogenous levels of its target protein and does not cross-react with other family members. |
供应商 | CST |
背景 | The Src family of protein tyrosine kinases, which includes Src, Lyn, Fyn, Yes, Lck, Blk, and Hck, are important in the regulation of growth and differentiation of eukaryotic cells (1). Src activity is regulated by tyrosine phosphorylation at two sites, but with opposing effects. While phosphorylation at Tyr416 in the activation loop of the kinase domain upregulates enzyme activity, phosphorylation at Tyr527 in the carboxy-terminal tail by Csk renders the enzyme less active (2). |
存放说明 | -20C |
参考文献 | Thomas, S.M. and Brugge, J.S. (1997) Annu Rev Cell Dev Biol 13, 513-609. Hunter, T. (1987) Cell 49, 1-4. Palacios, E.H. and Weiss, A. (2004) Oncogene 23, 7990-8000. Isosaka, T. et al. (2008) Eur. J. Neurosci. 28, 973-981. Seo, S. et al. (2001) J. Immunol. 166, 3710-3716. Summy, J.M. et al. (2003) J. Cell Sci. 116, 2585-2598. Werdich, X.Q. and Penn, J.S. (2005) Angiogenesis 8, 315-326. |
Western blot analysis of extracts from various cell lines using Yes Antibody #3201. | |
Western blot analysis of extracts from various cell lines using Yes Antibody. | |
Western blot analysis of extracts from Ramos and Jurkat cells using LcK (D88) XP® Rabbit mAb #2984.Western blot方法检测细胞提取物:Ramos、Jurkat 细胞,使用的抗体是LcK (D88) XP® Rabbit mAb #2984。 | |
Western blot analysis of extracts from various cell lines using Lyn (C13F9) Rabbit mAb #2796.Western blot方法检测细胞提取物:各种细胞系,使用的抗体是Lyn (C13F9) Rabbit mAb #2796。 | |
Western blot analysis of extracts from various cell lines using Fyn Antibody #4023.Western blot方法检测细胞提取物:各种细胞系,使用的抗体是Fyn Antibody #4023。 | |
Western blot analysis of extracts from various cell lines using Csk (C74C1) Rabbit mAb #4980.Western blot方法检测细胞提取物:各种细胞系,使用的抗体是Csk (C74C1) Rabbit mAb #4980。 | |
Western blot analysis of extracts from various cell lines using Src (32G6) Rabbit mAb #2123.Western blot方法检测细胞提取物:各种细胞系,使用的抗体是Src (32G6) Rabbit mAb #2123。 | |
Immunohistochemical analysis of paraffin-embedded human lung carcinoma using Lck (D88) XP® Rabbit mAb. | |
Immunohistochemical analysis of paraffin-embedded Colo205 (positive) (left) and HeLa (negative) (right) cell pellets using Lck (D88) XP® Rabbit mAb. | |
Immunohistochemical analysis of paraffin-embedded human tonsil using Lck (D88) XP® Rabbit mAb. | |
Immunohistochemical analysis of paraffin-embedded human lymphoma using Lck (D88) XP® Rabbit mAb. | |
Western blot analysis of extracts from Ramos and Jurkat cells using LcK (D88) XP® Rabbit mAb. | |
Western blot analysis of extracts from various cell lines using Csk (C74C1) Rabbit mAb. | |
Immunohistochemical analysis of paraffin-embedded non-hodgkins lymphoma using Lyn (C13F9) Rabbit mAb. | |
Immunohistochemical analysis of paraffin-embedded human tonsil tissue using Lyn (C13F9) Rabbit mAb in the presence of control peptide (left) and antigen specific peptide (right). |