HIF-1 alpha Antibody Pack
货号：
NB100-901IHC 基本售价：
5115.9 元 规格：
-
产品信息
概述| 货号 | NB100-901IHC |
| 反应种属 | Hu, Mu, RtSpecies Glossary |
| 应用 | WB, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP |
| 目标/特异性 | These antibodies are specific for HIF-1alpha. |
性能| 供应商 | Novus |
| 免疫原 | NB 100-131: Human HIF-1 alpha amino acids 329-530. NB100-123: Fusion protein containing amino acids 432-528 of human HIF-1alpha. NB100-449: peptide between residues 775 and the C-terminus (residue 826) of human HIF-1 alpha NB100-479: A fusion protein |
| 背景 | Our HIF-1 alpha sample pack provides a convenient way to determine the optimal HIF-1 alpha antibody for your specific species and tissues. Hypoxia contributes significantly to the pathophysiology of major categories of human disease, including myocardial and cerebral ischemia, cancer, pulmonary hypertension, congenital heart disease and chronic obstructive pulmonary disease. HIF-1 is a nuclear protein that activates gene transcription in response to reduced cellular 02 concentration. HIF-1 activates the transcription of EPO, VEGF, iNOS, heme oxygenase 1 and several other critical intracellular responses to hypoxia. HIF-1 is a heterodimer composed of HIF-1 alpha and HIF-1 beta subunits. Both subunits are induced by hypoxia and rapidly decay upon return to normoxia and are basic-helix-loop-helix-PAS proteins. Recent research indicates the ability to regulate hypoxia-inducible factors may be related to tumor-related angiogenesis in certain cancers. |
| 存放说明 | Store at 4C. Do not freeze. |
