CARD11/CARMA1 Antibody Pack
货号：
NBP2-25073 基本售价：
3341.2 元 规格：
-
产品信息
概述| 货号 | NBP2-25073 |
| 反应种属 | HuSpecies Glossary |
| 应用 | PEP-ELISA |
| 目标/特异性 | NP_115791 |
性能| 供应商 | Novus |
| 免疫原 | Format: Rabbit sera; Application: ELISA; Immunogen: amino acids 236-280 and 571-599Format: Rabbit sera; Application: ELISA; Immunogen: amino acids 1072-1099 |
| 背景 | CARMA1 is a 1154 amino acid protein playing a major role in the activation of NF-kappa-B through BCL10 and IKK. It contains a caspase-associated recruitment domain (CARD) and is thus included in the CARD protein family, a guanylate kinase-like domain and a PDZ (DHR) domain. The domain structure is similar to that of CARD14 protein and belongs to a class of proteins known as the membrane-associated guanylate kinase (MAGUK) family acting as molecular scaffolds. Binding of CARD11 and BCL10, a positive regulator of cell apoptosis and NF-kappaB activation, to each other occurs by CARD-CARD interaction and it stimulates the phosphorylation of BCL10. CARMA1 is detected in adult peripheral blood leukocytes, thymus, spleen and liver and in some cell lines except in HeLa S3, Molt-4, A549 and G431 cells. |
| 存放说明 | Store at -20C. Avoid freeze-thaw cycles. |
