TLR (Intracellular) Screening Antibody Pack
货号：
NBP2-25085 基本售价：
3162.7 元 规格：
-
产品信息
性能| 供应商 | Novus |
| 免疫原 | TLR3: 25 ug: WB, Flow, IP, IHC: H: Purified TLR7: 25 ug: WB, Flow, IHC, IP, IF/ICC: H, M: Purified TLR8: 25 ug: WB, Flow, IHC: H, M: Purified TLR9: 25 ug: WB, Flow, IHC, IF/ICC, CM: H, M, R, RM: Purified WB:Western Blot IHC:Immunohistochemistry IP:Immunoprecipitation CM:Confocal Microscopy FA-Neut Functional Assay Neutralization IF/ICC:Immunofluorescence/Immunocytochemistry D:Dog H:Human M:Mouse Mk:Monkey R:Rat RM:Rhesus Monkey |
| 背景 | The Toll-like receptor (TLR) family in mammals comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules. The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. TLR3, 7, 8, and 9 are expressed in the intracellular organelles. TLR7 and TLR8 have a common ligand, viral single-stranded RNA. TLR3 is activated by viral double-stranded RNA. TLR9 responds to bacterial unmethylated CpG DNA. Ten human homologs of TLRs (TLR1-10) have been described |
| 存放说明 | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
