PARP Enzyme High Specific Activity (1000 UN)
货号：
4668-100-01 基本售价：
3817.0 元 规格：
1000 U
产品信息
概述| 货号 | 4668-100-01 |
| 别名 | ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase); ADPRT 1; ADPRT; ADPRTADP-ribosyltransferase NAD(+); EC 2.4.2; EC 2.4.2.30; NAD(+) ADP-ribosyltransferase 1; PARP apoptosis; PARP1; PARP-1; PARPADPRT1; poly (ADP-ribose) polymerase 1; poly (ADP-ribose) polymerase family, member 1; poly [ADP-ribose] polymerase 1; poly(ADP-ribose) polymerase; poly(ADP-ribose) synthetase; poly(ADP-ribosyl)transferase; Poly[ADP-ribose] synthase 1; PPOL; PPOLpADPRT-1 |
全称 | Poly [ADP-ribose] Polymerase |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 142 (Human); 11545 (Mouse) |
| 背景 | PARP [Poly(ADP-ribose) Polymerase], also known as ADPRT and PPOL, is a 118-kDa enzyme that uses NAD as a substrate to catalyze the covalent transfer of ADP-ribose to a variety of nuclear protein acceptors. ADP ribosyltransferase is required for cellular repair, and PARP expression is induced by single-strand breaks in DNA. PARP is proteolytically cleaved by Caspase-3 into two fragments of 89- and 24-kDa in one of the hallmark events of apoptosis. |
| 运输条件 | Dry Ice |
| 存放说明 | -80℃ |
| 参考文献 | - Apoptosis
- Cancer Biomarkers
- Diabetic Peripheral Neuropathy
- DNA Modifying Enzymes
- HT PARP In Vivo Pharmacodynamic Assay II
- Immunotoxin-induced Apoptosis
- PAR & PARP Assays
- PARP Universal Colorimetric Assay
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