概述| 货号 | 4336-100-01 |
| 别名 | PAR |
全称 | Poly [ADP-ribose] Polymer |
性能| 供应商 | R&D Systems |
| 背景 | PARP [Poly(ADP-ribose) Polymerase], also known as ADPRT and PPOL, is a 118-kDa enzyme that uses NAD as a substrate to catalyze the covalent transfer of ADP-ribose to a variety of nuclear protein acceptors. ADP ribosyltransferase is required for cellular repair, and PARP expression is induced by single-strand breaks in DNA. PARP is proteolytically cleaved by Caspase-3 into two fragments of 89- and 24-kDa in one of the hallmark events of apoptosis. |
| 运输条件 | Blue Ice |
| 存放说明 | -80℃ |
| 参考文献 | - Apoptosis
- HT PARP In Vivo Pharmacodynamic Assay II
- Immunotoxin-induced Apoptosis
- PAR & PARP Assays
- PARP Universal Colorimetric Assay
|
