| 货号 | MAB691-500 |
| 别名 | CD136 antigen; CD136; CDw136c-met-related tyrosine kinase; EC 2.7.10; EC 2.7.10.1; macrophage stimulating 1 receptor (c-met-related tyrosine kinase); MSP receptor; MST1R; p185-Ron; Protein-tyrosine kinase 8; PTK8 protein tyrosine kinase 8; PTK8; Ron; RONmacrophage-stimulating protein receptor; soluble RON variant 1; soluble RON variant 2; soluble RON variant 3; soluble RON variant 4 | 全称 | Macrophage Stimulating Protein Receptor |
| 反应种属 | Human |
| 应用 | Blockade of Receptor-ligand Interaction |
| 目标/特异性 | Detects human MSP in direct ELISAs. In this format, this antibody shows less than 2% cross-reactivity with recombinant mouse (rm) MSP R. Recognizes an epitope found in the beta chain. |
| 使用方法 | Blockade of Receptor-ligand Interaction: In a functional ELISA, 0.05 - 0.2 μg/mL of this antibody will block 50% of the binding of 5 ng/mL of recombinant human MSP to immobilized recombinant human MSP R coated at 2 μg/mL (100 µL/well). At 3 μg/mL, this antibody will block >90% of the binding. |
| 来源 | Monoclonal Mouse IgG1 Clone # 99211 |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 4486 (Human); 19882 (Mouse) |
| 应用文献 | |
| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. CD molecules 2006--human cell differentiation molecules. | |
| 纯化方式 | Protein A or G purified from ascites |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant human MSP R Met1-Ser956 Accession # Q04912 |
| 内毒素水平 | <0.10 EU per 1 μg of the antibody by the LAL method. |
| 生物活性 | Human |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.5 mg/mL in sterile PBS. |
| 背景 | MSP R is a receptor tyrosine kinase that is translated as a singlepolypeptide and then proteolytically cleaved to yield a matureheterodimer consisting of an extracellular 35 kDa alpha chain disulfide-linked to a membrane-spanning 150 kDa beta chain. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 |
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