Ms CD140A NALE APA5 500ug
货号：
562171 基本售价：
5840.0 元 规格：
500ug
产品信息
概述| 货号 | 562171 |
| 描述 | The APA5 antibody monoclonal antibody specifically binds to CD140a, the Platelet-Derived Growth Factor Receptor alpha chain (PDGFR-a, PDGFR-α). CD140a is a receptor tyrosine kinase that is widely expressed on cells of mesenchymal origin in the embryo and adult. CD140a is expressed on several other cell types during embryonic development, but not on hematopoietic cells. CD140a binds to PDGF A and B chains, in contrast to PDGFR-b (CD140b) that binds only to the PDGF B chain. Biologically active PDGF is a disulphide-linked dimer, forming the AA, AB, and BB isoforms. Ligand binding to the PDGF Receptor induces the formation of receptor dimers (aa, ab, or bb), autophosphorylation, and internalization. The APA5 antibody has been demonstrated to block binding ofPDGF-AA to PDGFR-a-expressing cells in vitroand to block some PDGF-mediated developmental events in vivo. |
| 别名 | Pdgfra; Pdgfr2; PDGF-R alpha; Platelet derived growth factor receptor alpha |
| 同种亚型 | Rat WF, also known as Wistar Furth IgG2a |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Mouse PDGF Receptor α chain |
| 标记 | NA/LE |
| 存放说明 | Store undiluted at 4°C.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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| 存储溶液 | No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2µm sterile filtered. Endotoxin level is ≤0.01 EU/µg (≤0.001 ng/µg) of protein as determined by the LAL assay. |
| 浓度 | 1.0 mg/ml |
