Human P-Selectin/CD62P MAb (Cl 9E1) (200 UG)【科瑞奥博】

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Human P-Selectin/CD62P MAb (Cl 9E1) (200 UG)

货号： BBA30 基本售价： 4659.8 元规格： 200 ug

产品信息

概述
货号	BBA30
别名	CD62P antigen; CD62P; FLJ45155; GMP140; GRMP; PADGEM; PADGEMantigen CD62); PSEL; selectin P (granule membrane protein 140kDa, antigen CD62); SELP
反应种属	Human
应用	Immunohistochemistry,Adhesion Blockade
目标/特异性	This antibody binds to CHO cells transfected with human P-Selectin but not to CHO cells transfected with either human E-Selectin or human L-Selectin.
使用方法	Immunohistochemistry: 8-25 µg/mL Adhesion Blockade: The adhesion of U937 human histiocytic lymphoma cells (5 x 10⁴ cells/well) to immobilized Recombinant Human P-Selectin/CD62P (Catalog # ADP3, 10 µg/mL, 100 µL/well) was maximally inhibited (80-100%) by 1 µg/mL of the antibody.
来源	Monoclonal Mouse IgG₁ Clone # 9E1
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	6403 (Human); 20344 (Mouse)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. A role for the L-selectin adhesion system in mediating cytotrophoblast emigration from the placenta. Authors: Prakobphol A, Genbacev O, Gormley M, Kapidzic M, Fisher SJ Dev. Biol., 2006;298(1):107-17. Species: Human Sample Type: Whole Tissue Application: IHC Frozen P-Selectin-mediated acute inflammation can be blocked by chemically modified heparin, RO-heparin. Authors: Gao Y, Li N, Fei R, Chen Z, Zheng S, Zeng X Mol. Cells, 2005;19(3):350-5. Species: Human Sample Type: Whole Cells Application: Neut
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	Recombinant human P-Selectin Extracellular domain
内毒素水平	<0.10 EU per 1 μg of the antibody by the LAL method.
生物活性	Human
标记	Unconjugated
溶解方法	Sterile PBS to a final concentration of 0.5 mg/mL.
背景	P-Selectin, also known as GMP-140 and PADGEM, is a transmembraneglycoprotein expressed by activated platelets and endothelial cells.P-Selectin binds to PSGL-1 on myeloid cells, neutrophils, monocytes,and lymphocytes. P-Selectin plays a role in the adhesion of leukocytesand neutrophils to the endothelium.
运输条件	Blue Ice
存放说明	-20℃
参考文献	Endothelial Cell Markers Endothelial Cell Markers and Adhesion Molecules in Angiogenesis Human CD Marker Products ICC / IHC Images: P-Selectin/CD62P Lectins Mini-review: Adhesion Molecules I Mini-review: Adhesion Molecules II Mini-review: Multiple Sclerosis: Immune Cell Access to the Central Nervous System Platelets Regulatory T Cells (Tregs) Selectins

参考图片

P-Selectin/CD62P in Human Breast Cancer Tissue. P‑Selectin/CD62P was detected in immersion fixed paraffin-embedded sections of human breast cancer tissue using 25 µg/mL Human P‑Selectin/CD62P Monoclonal Antibody (Catalog # BBA30) overnight at 4 °C. Tissue was stained with the Anti-Mouse HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS002) and counterstained with hematoxylin (blue). View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.