| 货号 | BBA29-200 |
| 别名 | CD50 antigen; CD50; CDW50CDw50; ICAM-3; ICAM-Rintercellular adhesion molecule-3; intercellular adhesion molecule 3 | 全称 | Intercellular Adhesion Molecule 3 |
| 反应种属 | Human |
| 应用 | Western Blot(1 µg/mL) Flow Cytometry(2.5 µg/106cells) |
| 目标/特异性 | Detects human ICAM-3/CD50 in Western blots. Does not cross-react with recombinant human (rh) ICAM-1 or rhVCAM-1. |
| 使用方法 | Western Blot: 1 µg/mL Flow Cytometry: 2.5 µg/106cells Adhesion Blockade: Bossy, D. et al. (1995) Eur. J. Immunol. 25:459. |
| 来源 | Monoclonal Mouse IgG1 Clone # Cal 3.10 |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 3385 (Human) |
| 应用文献 | |
| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Macrophage recognition of ICAM-3 on apoptotic leukocytes. | |
| 纯化方式 | Protein A or G purified from hybridoma culture supernatant |
| 免疫原 | Recombinant human ICAM-3/CD50 Fc Chimera |
| 内毒素水平 | <0.10 EU per 1 μg of the antibody by the LAL method. |
| 生物活性 | Human |
| 标记 | Unconjugated |
| 溶解方法 | Sterile PBS to a final concentration of 0.5 mg/mL. |
| 背景 | Intercellular Adhesion Molecule-3 (ICAM-3), a member of the immunoglobulin superfamily, binds the leukocyte integrins LFA-1 (CD11a/CD18) and alpha d/ beta 2. ICAM-3 is expressed on leukocytes and epidermal Langerhans cells. It may play an important role in T cell stimulation by Langerhans cells. ICAM-3 has not been identified in mice. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 |
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