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货号： bs-11228R-Cy5.5 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-11228R-Cy5.5
- 英文名称
- Anti-Phospho-JunB (Thr102 + Thr104)/Cy5.5
- 中文名称
- Cy5.5标记的磷酸化活化蛋白激酶B抗体
- 别 名
- Phospho-JunB (Thr102/Thr104); P-JunB (Phospho Thr102/Thr104); Activator protein 1; AP 1; AP1; Jun B; Jun B proto oncogene; Jun B protooncogene; JunB proto oncogene; JunB protoncogene 9; JunB protooncogene; Transcription factor jun B; Transcription factor junB; JUNB_HUMAN; Transcription factor jun-B; Transcription factor junB.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 产品类型
- 磷酸化抗体
- 研究领域
- 肿瘤 转录调节因子 激酶和磷酸酶
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Cow, Horse, Guinea Pig,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 38kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated Synthesised phosphopeptide derived from human JunB around the phosphorylation site of Thr102/Thr104 [TT(p-T)P(p-T)PP]
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The cJun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus vjun oncogene. JunB and JunD have been shown to be almost identical to cJun in their C terminal regions, which are involved in dimerization and DNA binding, whereas their N terminal domains, which are involved in transcriptional activation, diverge. JunB is a transcription factor involved in regulating gene activity following the primary growth factor response. It binds to the DNA sequence 5-TGA[CG]TCA-3.
Function:
Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5-TGA[CG]TCA-3.
Subunit:
Binds DNA as a homodimer or as a heterodimer with another member of the Jun/Fos family. Interacts with ITCH (via its WW domains).
Subcellular Location:
Nucleus.
Post-translational modifications:
Ubiquitinated by ITCH, leading to its degradation.
Similarity:
Belongs to the bZIP family. Jun subfamily.
Contains 1 bZIP (basic-leucine zipper) domain.
Database links:Entrez Gene: 3726Human
Entrez Gene: 16477Mouse
Entrez Gene: 24517Rat
Omim: 165161Human
SwissProt: P17275Human
SwissProt: P09450Mouse
SwissProt: P24898Rat
Unigene: 25292Human
Unigene: 1167Mouse
Unigene: 470093Mouse
Unigene: 15806Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.