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货号： bs-19230R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-19230R
- 英文名称
- NFYB
- 中文名称
- 核转录因子YB抗体
- 别 名
- CAAT box DNA binding protein subunit B; CBF A; CBF B; CCAAT binding transcription factor subunit A; HAP 3; HAP3; NF Y protein chain B; NF YB; NFYB; Nuclear transcription factor Y beta; Nuclear transcription factor Y subunit B; Nuclear transcription factor Y subunit beta.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 信号转导 转录调节因子 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Mouse, Horse, Xenopus laevis.
- 产品应用
- ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 23kDa
- 细胞定位
- 细胞核
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human NFYB:1-100/207
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence; protein sequence alignments and experiments with mutants. [provided by RefSeq, Jul 2008]
Function:
Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters, for example in type 1 collagen, albumin and beta-actin genes.
Subcellular Location:
Nucleus.
Similarity:
Belongs to the NFYB/HAP3 subunit family.
SWISS:
P25208
Gene ID:
4801
Database links:Entrez Gene: 396205Chicken
Entrez Gene: 614382Cow
Entrez Gene: 4801Human
Entrez Gene: 18045Mouse
Entrez Gene: 100157587Pig
Entrez Gene: 25336Rat
Entrez Gene: 399126 Xenopus laevis
Omim: 189904Human
SwissProt: P25207Chicken
SwissProt: Q32KW0Cow
SwissProt: P25208Human
SwissProt: P63139Mouse
SwissProt: P63140Rat
SwissProt: Q5FVT0Rat
SwissProt: 100157587 Xenopus laevis
SwissProt: P25211 Xenopus laevis
Unigene: 84928Human
Unigene: 245998Mouse
Unigene: 90077Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.