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货号： bs-24130R-Cy5 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-24130R-Cy5
- 英文名称
- Anti-SLC5A11/Cy5
- 中文名称
- Cy5标记的碳酸氢钠协同转运蛋白4-A11抗体
- 别 名
- homolog of rabbit KST1; KST1; Na(+)/myo-inositol cotransporter 2; na+/myo-inositol cotransporter 2; putative sodium-coupled cotransporter RKST1; RKST1; SC5AB_MOUSE; SGLT6; SLC5A11; SMIT2; sodium-dependent glucose cotransporter; sodium/glucose cotransporter KST1; sodium/myo-inositol cotransporter 2; Sodium/myo-inositol transporter 2; solute carrier family 5 (sodium/glucose cotransporter), member 11; solute carrier family 5 member 11.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 74kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 2mg/1ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from mouse SLC5A11
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Cotransporters, such as SLC5A11, represent a major class of proteins that make use of ion gradients to drive active transport for the cellular accumulation of nutrients, neurotransmitters, osmolytes, and ions Roll et al. (2002) [PubMed 12039040].[supplied by OMIM, Mar 2008]
Function:
Involved in the sodium-dependent cotransport of myo-inositol (MI) with a Na(+):MI stoichiometry of 2:1. Exclusively responsible for apical MI transport and absorption in intestine. Also can transport D-chiro-inositol (DCI) but not L-fructose. Exhibits stereospecific cotransport of both D-glucose and D-xylose. May induce apoptosis through the TNF-alpha, PDCD1 pathway. May play a role in the regulation of MI concentration in serum, involving reabsorption in at least the proximal tubule of the kidney.
Subcellular Location:
Membrane.
Tissue Specificity:
Highest expression in heart, skeletal muscle, kidney, liver and placenta. Weaker expression in brain, colon, spleen, lung and peripheral blood leukocytes.
Similarity:
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
Database links:Entrez Gene: 115584 Human
Entrez Gene: 233836 Mouse
Omim: 610238 Human
SwissProt: Q8WWX8 Human
SwissProt:Q8K0E3 Mouse
Unigene:164118 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.