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货号： bs-19171R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-19171R
- 英文名称
- MYO3A
- 中文名称
- 肌球蛋白3A抗体
- 别 名
- deafness, autosomal recessive 30; DFNB30; Myo3a; MYO3A_HUMAN; Myosin IIIA; Myosin-IIIa.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 细胞生物 免疫学 神经生物学 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse,
- 产品应用
- ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 186kDa
- 细胞定位
- 细胞浆
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human MYO3A:1081-1180/1616
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
The protein encoded by this gene belongs to the myosin superfamily. Myosins are actin-dependent motor proteins and are categorized into conventional myosins (class II) and unconventional myosins (classes I and III through XV) based on their variable C-terminal cargo-binding domains. Class III myosins, such as this one, have a kinase domain N-terminal to the conserved N-terminal motor domains and are expressed in photoreceptors. The protein encoded by this gene plays an important role in hearing in humans. Three different recessive, loss of function mutations in the encoded protein have been shown to cause nonsyndromic progressive hearing loss. Expression of this gene is highly restricted, with the strongest expression in retina and cochlea. [provided by RefSeq, Jul 2008]
Function:
Probable actin-based motor with a protein kinase activity. Probably plays a role in vision and hearing.
Subcellular Location:
Cytoplasm, cytoskeleton.
Tissue Specificity:
Strongest expression in retina, retinal pigment epithelial cells, cochlea and pancreas.
DISEASE:
Deafness, autosomal recessive, 30
Similarity:
In the N-terminal section; belongs to the protein kinase superfamily.
STE Ser/Thr protein kinase family.
Contains 3 IQ domains.
Contains 1 myosin head-like domain.
Contains 1 protein kinase domain.
SWISS:
Q8NEV4
Gene ID:
53904
Database links:Entrez Gene: 53904Human
Omim: 606808Human
SwissProt: Q8NEV4Human
Unigene: 662630Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.