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货号： bs-19050R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-19050R
- 英文名称
- NCKX2
- 中文名称
- 视网膜钠/钾/钙交换体2抗体
- 别 名
- Na(+)/K(+)/Ca(2+) exchange protein 2; Na(+)/K(+)/Ca(2+)-exchange protein 2; NCKX 2; NCKX2_HUMAN; OTTHUMP00000045115; Retinal cone Na Ca+K exchanger; Retinal cone Na-Ca+K exchanger; SLC24A2; Sodium/potassium/calcium exchanger 2; solute carrier family 24 (sodium/potassium/calcium exchanger) member 2; Solute carrier family 24 member 2.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 细胞生物 神经生物学 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Rat, Dog, Pig, Cow, Horse, Sheep,
- 产品应用
- ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 74kDa
- 细胞定位
- 细胞膜
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human NCKX2:71-170/661 <Extracellular>
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
This gene encodes a member of the calcium/cation antiporter superfamily of transport proteins. The encoded protein belongs to the SLC24 branch of exchangers, which can mediate the extrusion of one Ca2+ ion and one K+ ion in exchange for four Na+ ions. This family member is a retinal cone/brain exchanger that can mediate a light-induced decrease in free Ca2+ concentration. This protein may also play a neuroprotective role during ischemic brain injury. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]
Function:
Critical component of the visual transduction cascade, controlling the calcium concentration of outer segments during light and darkness. Light causes a rapid lowering of cytosolic free calcium in the outer segment of both retinal rod and cone photoreceptors and the light-induced lowering of calcium is caused by extrusion via this protein which plays a key role in the process of light adaptation. Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+).
Subcellular Location:
Membrane.
Similarity:
Belongs to the sodium/potassium/calcium exchanger family. SLC24A subfamily.
SWISS:
Q9UI40
Gene ID:
25769
Database links:Entrez Gene: 25769Human
Entrez Gene: 76376Mouse
Entrez Gene: 84550Rat
Omim: 609838Human
SwissProt: Q9UI40Human
SwissProt: O54701Rat
Unigene: 283014Human
Unigene: 208755Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.