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货号： bs-18935R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-18935R
- 英文名称
- MICALL1/MIRab13
- 中文名称
- MICAL样蛋白1抗体
- 别 名
- DKFZp686M2226; FLJ45921; KIAA1668; MICAL-L1; MICAL-like 1; MICAL-like protein 1; Micall1; MILK1_HUMAN; MIRab13; Molecule interacting with Rab13.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 细胞生物 免疫学 神经生物学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Cow, Horse, Sheep,
- 产品应用
- ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 93kDa
- 细胞定位
- 细胞浆
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human MICALL1/MIRab13:401-500/863
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
MIRAB13 is an 863 amino acid cytoplasmic protein belonging to the MICAL family that contains one CH (calponin-homology) domain, one LIM zinc-binding domain and two unique asparagine-proline-phenylalanine motifs, which are known to interact with EH-domains. Considered a cytoskeletal regulator, MIRAB13 associates with Rab 13, a tight junction protein, as well as EHD, a key regulator of ligand-induced endocytosis and recycling. MIRAB13 is encoded by a gene located on human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia.
Function:
May be a cytoskeletal regulator.
Subcellular Location:
Cytoplasm >cytoskeleton.
Similarity:
Contains 1 CH (calponin-homology) domain.
Contains 1 LIM zinc-binding domain.
SWISS:
N3F8
Gene ID:
85377
Database links:Entrez Gene: 85377Human
SwissProt: Q8N3F8Human
Unigene: 517610Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.