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货号: bs-18883R 基本售价: 1380.0 元 规格: 100ul
- 规格:100ul
- 价格:1380.00元
- 规格:200ul
- 价格:2200.00元
产品信息
- 产品编号
- bs-18883R
- 英文名称
- PDE10A
- 中文名称
- 磷酸二酯酶10A抗体
- 别 名
- 5-cyclic phosphodiesterase 10A; cAMP and cAMP inhibited cGMP 35 cyclic phosphodiesterase 10A; cAMP and cAMP-inhibited cGMP 3; cAMP and cAMP-inhibited cGMP 35-cyclic phosphodiesterase 10A; FLJ11894; HSPDE 10A; HSPDE10A; PDE 10A; PDE10_HUMAN; Pde10a; Phosphodiesterase 10A; Phosphodiesterase 10A1.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 细胞生物 神经生物学 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
- 产品应用
- IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 88kDa
- 细胞定位
- 细胞浆
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human PDE10A:241-340/779
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5 monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2011]
Function:
Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient with cAMP as substrate.
Subcellular Location:
Cytoplasm. Located mostly to soluble cellular fractions.
Tissue Specificity:
Abundant in the putamen and caudate nucleus regions of brain and testis, moderately expressed in the thyroid gland, pituitary gland, thalamus and cerebellum.
Similarity:
Belongs to the cyclic nucleotide phosphodiesterase family.Contains 2 GAF domains.
SWISS:
Q9Y233
Gene ID:
10846
Database links:Entrez Gene: 10846Human
Entrez Gene: 23984Mouse
Entrez Gene: 63885Rat
Omim: 610652Human
SwissProt: Q9Y233Human
SwissProt: Q8CA95Mouse
SwissProt: Q9QYJ6Rat
Unigene: 348762Human
Unigene: 87161Mouse
Unigene: 44869Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.