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货号： bs-18838R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-18838R
- 英文名称
- PTP mu
- 中文名称
- 蛋白酪氨酸磷酸酶亩mu抗体
- 别 名
- hR PTPu; Protein tyrosine phosphatase mu; Protein tyrosine phosphatase receptor type M; Protein tyrosine phosphatase receptor type mu polypeptide; Protein-tyrosine phosphatase mu; PTPRL1; Ptprm; PTPRM_HUMAN; R PTP mu; R-PTP-mu; Receptor type tyrosine protein phosphatase mu; Receptor-type tyrosine-protein phosphatase mu; RPTPM; RPTPU.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 细胞生物 信号转导 激酶和磷酸酶
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Cow,
- 产品应用
- ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 162kDa
- 细胞定位
- 细胞膜
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human PTP mu:201-300/1452 <Extracellular>
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms. [provided by RefSeq, Jul 2008]
Function:
Involved in cell-cell adhesion through homophilic interactions. May play a key role in signal transduction and growth control.
Subcellular Location:
Membrane.
Similarity:
Belongs to the protein-tyrosine phosphatase family.
Receptor class 2B subfamily.
Contains 4 fibronectin type-III domains.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 MAM domain.
Contains 2 tyrosine-protein phosphatase domains.
SWISS:
P28827
Gene ID:
5797
Database links:Entrez Gene: 5797Human
Entrez Gene: 536092Cow
Entrez Gene: 480203Dog
Entrez Gene: 19274Mouse
Entrez Gene: 100173948Orangutan
Entrez Gene: 29616Rat
Omim: 176888Human
SwissProt: P28827Human
SwissProt: P28828Mouse
Unigene: 49774Human
Unigene: 311809Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.