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货号： bs-16984R-Cy5 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-16984R-Cy5
- 英文名称
- Anti-KIAA0859/Cy5
- 中文名称
- Cy5标记的KIAA0859蛋白抗体
- 别 名
- 5630401D24Rik; CGI-01; MET13_HUMAN; Methyltransferase-like protein 13; Mettl13.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Dog, Pig, Cow, Horse, Rabbit, Rhesus monkey, Gorilla, Orangutan
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 79kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human KIAA0859
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
METTL13 is a 699 amino acid protein that exists as five alternatively spliced isoforms that are encoded by a gene that maps to human chromosome 1. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.
Similarity:
Belongs to the methyltransferase superfamily.
Database links:Entrez Gene: 490342Dog
Entrez Gene: 51603Human
Entrez Gene: 71449Mouse
Entrez Gene: 100512915Pig
Entrez Gene: 100342720Rabbit
SwissProt: Q8N6R0Human
SwissProt: Q91YR5Mouse
Unigene: 494705Human
Unigene: 270569Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.