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货号： bs-16867R-Cy5 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-16867R-Cy5
- 英文名称
- Anti-Kv3.2/Cy5
- 中文名称
- Cy5标记的电压门控钾通道Kv3.2抗体
- 别 名
- KCNC2; KSHIIIA; Kv 3.2; Kv3.2d voltage gated potassium channel; Potassium channel Kv3.2; Shaw related voltage gated potassium channel protein 2.KCNC2_HUMAN
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 神经生物学 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 70kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Kv3.2
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Potassium channels contribute to maintaining cell volume, membrane potential, neuronal excitability and the secretion of transmitters, salt and hormones. Two families of potassium channels have been identified. One family includes the inwardly rectifying potassium channels whereas, the other family includes: voltage sensing (KV); big conductance, calcium activated (BKca); and small conductance, calcium activated (SK) potassium channels. Kv3.2 functions as a delayed rectifier type K+ channel activated by large membrane depolarizations.
Function:
Mediates the voltage-dependent potassium ionpermeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. Channel properties are modulated by subunit assembly (By similarity)
Subunit:
The potassium channel is probably composed of a homo- orheterotetrameric complex of pore-forming subunits that canassociate with modulating accessory subunits
Subcellular Location:
Membrane; Multi-pass membrane protein.
Similarity:
Belongs to the potassium channel family.
Database links:- Entrez Gene: 3747 Human
- Entrez Gene: 246153 Rat
- Omim: 176256 Human
- SwissProt: Q86W09 Human
- SwissProt: Q96PR1 Human
- SwissProt: P22462 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.