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货号： bs-16667R-Cy5 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-16667R-Cy5
- 英文名称
- Anti-INPP4A/Cy5
- 中文名称
- Cy5标记的聚磷酸肌醇磷酸酶4A抗体
- 别 名
- Type I 4-phosphatase;107kDa; 4-bisphosphate 4-phosphatase; 9630012D15; D130048C09Rik; Inositol polyphosphate 4 phosphatase type I 107kDa; Inositol polyphosphate 4 phosphatase type I; Inositol polyphosphate 4-phosphatase type I; INP4A_HUMAN; INPP4; Inpp4a; OTTHUMP00000203138; OTTHUMP00000203139; OTTHUMP00000203141; OTTHUMP00000225217; R74740; TVAS1; Type I inositol 3 4 bisphosphate 4 phosphatase; Type I inositol 3,4 bisphosphate 4 phosphatase; Type I inositol-3.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 神经生物学 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, Xenopus laevis
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 110kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human INPP4A
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The inositol polyphosphate 4-phosphatases selectively remove the phosphate from the 4-position of various phosphatidylinositols, which generate second messengers in response to extracellular signals. Both the type I and type II 4-phosphatases catalyze the hydrolysis of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4-trisphosphate, and inositol 3,4-bisphosphate. Type I and type II 4-phosphatases are both alternatively spliced into two isoforms, a and b, which have been detected in human platelets, rat brain, heart, skeletal muscle and spleen; and all isoforms contain a conserved motif CKSAKDRT, which contains the active site consensus sequence C-X5-R. Both type I and II 4-phosphatases are thought to regulate the level of intracellular calcium by acting as signal terminating enzymes.
Function:
Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4-trisphosphate and inositol 3,4-bisphosphate.
Tissue Specificity:
Isoform 1 is expressed in the platelets, MEG-01 megakaryocytes and Jurkat T-cells. Isoform 2 is expressed in the brain.
Similarity:
Belongs to the inositol-3,4-bisphosphate 4-phosphatase family.
Contains 1 C2 domain.
Database links:Entrez Gene: 3631Human
Entrez Gene: 269180Mouse
Entrez Gene: 100233232Pig
Entrez Gene: 80849Rat
Entrez Gene: 734645 Xenopus laevis
Omim: 600916Human
SwissProt: Q96PE3Human
SwissProt: Q9EPW0Mouse
SwissProt: Q62784Rat
Unigene: 469386Human
Unigene: 5294Mouse
Unigene: 11215Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.