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货号： bs-18145R 基本售价： 1580.0 元 规格： 100ul
产品信息
- 产品编号
- bs-18145R
- 英文名称
- phospho-IL2 Receptor alpha (Ser268)
- 中文名称
- 磷酸化白介素2受体α链抗体
- 别 名
- IL2 Receptor alpha (phospho S268); p-IL2 Receptor alpha (phospho S268); Interleukin 2 receptor alpha chain; CD 25; CD25; CD25 antigen; IDDM10; IL 2 RA; IL 2 receptor alpha subunit; IL 2R; IL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2 RA; IL2-RA; IL2R; IL2RA; IL2RA_HUMAN; IL2RAC; Interleukin 2 Receptor Alpha; Interleukin 2 receptor alpha chain; Interleukin 2 receptor; Interleukin-2 receptor subunit alpha; Ly43; p55; T Cell Growth Factor Receptor; TAC; TAC Antigen; TCGFR.
- 规格价格
- 100ul/1580元购买 大包装/询价
- 说 明 书
- 100ul
- 产品类型
- 磷酸化抗体
- 研究领域
- 细胞生物 免疫学 t-淋巴细胞 细胞膜蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human,
- 产品应用
- WB=1:500-2000 ELISA=1:500-1000 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 28kDa
- 细胞定位
- 细胞膜
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthesised phosphopeptide derived from humanIL2 Receptor alpha around the phosphorylation site of Ser268:RK(p-S)RR
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.[provided by RefSeq, Nov 2009]
Function:
Receptor for interleukin-2.
Subcellular Location:
Membrane.
DISEASE:
Genetic variations in IL2RA are associated with susceptibility to diabetes mellitus insulin-dependent type 10 (IDDM10) [MIM:601942]. A multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy. Clinical fetaures are polydipsia, polyphagia and polyuria which result from hyperglycemia-induced osmotic diuresis and secondary thirst. These derangements result in long-term complications that affect the eyes, kidneys, nerves, and blood vessels.
Similarity:
Contains 2 Sushi (CCP/SCR) domains.
SWISS:
P01589
Gene ID:
3559
Database links:Entrez Gene: 3559Human
Entrez Gene: 16184Mouse
Omim: 147730Human
SwissProt: P01589Human
SwissProt: P01590Mouse
Unigene: 231367Human
Unigene: 915Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.