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货号： bs-17725R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-17725R
- 英文名称
- MOSC2
- 中文名称
- MOSC2蛋白抗体
- 别 名
- FLJ20605; mitochondrial; MOCO sulphurase C-terminal domain containing 2; MOSC domain-containing protein 2; MOSC2; MOSC2_HUMAN; RP11-270A6.1.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 肿瘤 细胞生物 信号转导 新陈代谢
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 35kDa
- 细胞定位
- 细胞浆
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human MOSC2:101-200/335
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
MOSC2 is a 335 amino acid peripheral membrane protein that localizes to the mitochondria. Containing a MOSC domain, MOSC2 utilizes molybdenum as a cofactor and is a component of the benzamidoxime prodrug-converting complex that is comprised of cytochrome b5, NADH-cytochrome b5 reductase (CYB5R3). CYB5R3 belongs to the flavoprotein pyridine nucleotide cytochrome reductase family and is involved in the desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism and, in erythrocytes, methemoglobin reduction. Benzamidoxime prodrug-converting complex is required to reduce N-hydroxylated structures, such as benzamidoxime prodrug. MOSC2 exists as two alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 1q41.
Function:
Catalytic component of the benzamidoxime prodrug-converting complex, a complex required to reduce N-hydroxylated structures, such as benzamidoxime prodrug. Benzamidoxime is an amidine prodrug produced by N-hydroxylation which is used to enhance bioavailability and increase intestinal absorption. It is then reduced into benzamidine, its active amidine, by the benzamidoxime prodrug-converting complex.
Subcellular Location:
Mitochondrion outer membrane.
Similarity:
Contains 1 MOSC domain.
SWISS:
Q969Z3
Gene ID:
54996
Database links:Entrez Gene: 54996Human
Entrez Gene: 67247Mouse
SwissProt: Q969Z3Human
SwissProt: Q922Q1Mouse
Unigene: 369042Human
Unigene: 177724Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.