产品中心
当前位置：首页>产品中心Anti-SKIV2L2
货号： bs-17510R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-17510R
- 英文名称
- SKIV2L2
- 中文名称
- ATP依赖的解旋酶SKIV2L2抗体
- 别 名
- 2610528A15Rik; ATP dependent helicase SKIV2L2; Dob1; SK2L2_HUMAN; KIAA0052; MGC142069; mKIAA0052; Mtr4; superkiller viralicidic activity 2 like 2 (S. cerevisiae); Superkiller viralicidic activity 2 like 2.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 细胞生物 转录调节因子 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep,
- 产品应用
- ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 117kDa
- 细胞定位
- 细胞核
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human SKIV2L2:901-1042/1042
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
SKIV2L2, or superkiller viralicidic activity 2 like 2, may be involved in pre-mRNA splicing. SKIV2L2 is an exosome-associated protein and may be involved in the recruitment of the exosome to pre-rRNA, to mediate the 3 end processing of 5.8S rRNA.
Function:
May be involved in pre-mRNA splicing. Associated with the RNA exosome complex and involved in the 3-processing of the 7S pre-RNA to the mature 5.8S rRNA.
Subunit:
Component of a TRAMP-like complex, an ATP-dependent exosome regulatory complex consisting of an helicase (SKIV2L2/MTR4), an oligadenylate polymerase (PAPD5 or PAPD7), and a substrate specific RNA-binding factor (ZCCHC7 or ZCCHC8). Several TRAMP-like complexes exist with specific compositions and are associated with nuclear, or nucleolar RNA exosomes. Identified in the spliceosome C complex.
Subcellular Location:
Nucleus, nucleoplasm. Nucleus, nucleolus.
Similarity:
Belongs to the helicase family. SKI2 subfamily.
Contains 1 helicase ATP-binding domain.
Contains 1 helicase C-terminal domain.
SWISS:
P42285
Gene ID:
23517
Database links:Entrez Gene: 23517Human
Entrez Gene: 72198Mouse
SwissProt: P42285Human
SwissProt: Q9CZU3Mouse
Unigene: 274531Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.