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货号： bs-17415R 基本售价： 1580.0 元 规格： 100ul
产品信息
- 产品编号
- bs-17415R
- 英文名称
- Histone H1 (acetyl K25)
- 中文名称
- 乙酰化组蛋白H1抗体
- 别 名
- H10; H10_HUMAN; h1f0; H1FV; Histone H1; Histone H1(0); Histone H10; Histone H5; MGC5241; N-terminally processed.
- 规格价格
- 100ul/1580元购买 大包装/询价
- 说 明 书
- 100ul
- 产品类型
- 乙酰化抗体
- 研究领域
- 细胞生物 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Cow, Sheep,
- 产品应用
- ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 21kDa
- 细胞定位
- 细胞核
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated Synthesised acetylpeptide derived from human Histone H1 around the acetylation site of K25:
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-independent histone that is a member of the histone H1 family. [provided by RefSeq, Oct 2015]
Function:
Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. The H1F0 histones are found in cells that are in terminal stages of differentiation or that have low rates of cell division.
Subcellular Location:
Nucleus. Chromosome. The RNA edited version has been localized to nuclear speckles. During mitosis, it appears in the vicinity of condensed chromosomes.
Post-translational modifications:
Phosphorylated on Ser-17 in RNA edited version.
Similarity:
Belongs to the histone H1/H5 family.Contains 1 H15 (linker histone H1/H5 globular) domain.
SWISS:
P07305
Gene ID:
3005
Database links:Entrez Gene: 3005 Human
Entrez Gene: 14958 Mouse
Entrez Gene: 24437 Rat
Omim: 142708 Human
SwissProt: P07305 Human
SwissProt: P10922 Mouse
SwissProt: P43278 Rat
Unigene: 745024 Human
Unigene: 24350 Mouse
Unigene: 3129 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.