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货号： bs-17390R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-17390R
- 英文名称
- HS3ST3A1
- 中文名称
- HS3ST3A1蛋白抗体
- 别 名
- 3-OST-3A; 30ST3A1; 3OST3A1; h3 OST 3A; h3-OST-3A; heparan sulfate (glucosamine) 3 O sulfotransferase 3A1; Heparan sulfate 3 O sulfotransferase 3A1; Heparan sulfate 3-O-sulfotransferase 3A1; Heparan sulfate D glucosaminyl 3 O sulfotransferase 3A1; Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1; Heparan sulfate glucosamine 3-O-sulfotransferase 3A1; HS3SA_HUMAN; HS3ST3A1.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 细胞生物 信号转导 新陈代谢
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 45kDa
- 细胞定位
- 细胞浆
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human HS3ST3A1:1-100/406 <Cytoplasmic>
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. The enzyme encoded by this gene is a member of the heparan sulfate biosynthetic enzyme family. It is a type II integral membrane protein and possesses heparan sulfate glucosaminyl 3-O-sulfotransferase activity. The sulfotransferase domain of this enzyme is highly similar to the same domain of heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1, and these two enzymes sulfate an identical disaccharide. This gene is widely expressed, with the most abundant expression in liver and placenta. [provided by RefSeq, Jul 2008]
Function:
Sulfotransferase that utilizes 3-phospho-5-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to an N-unsubstituted glucosamine linked to a 2-O-sulfo iduronic acid unit on heparan sulfate. Catalyzes the O-sulfation of glucosamine in IdoUA2S-GlcNS and also in IdoUA2S-GlcNH2. The substrate-specific O-sulfation generates an enzyme-modified heparan sulfate which acts as a binding receptor to Herpes simplex virus-1 (HSV-1) and permits its entry. Unlike 3-OST-1, does not convert non-anticoagulant heparan sulfate to anticoagulant heparan sulfate.
Subcellular Location:
Golgi apparatus membrane.
Tissue Specificity:
Ubiquitous. Most abundant in heart and placenta, followed by liver and kidney.
Similarity:
Belongs to the sulfotransferase 1 family.
SWISS:
Q9Y663
Gene ID:
9955
Database links:Entrez Gene: 9955Human
GenBank: NM_006042.1Human
Omim: 604057Human
SwissProt: Q9Y663Human
Unigene: 462270Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.