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货号： bs-17364R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-17364R
- 英文名称
- HOXB7
- 中文名称
- 同源盒蛋白B7抗体
- 别 名
- AI325018; HHO C1; HHO.C1; homeo box B7; homeo box c1 protein; Homeobox 2C; homeobox B7; Homeobox protein HHO.C1; Homeobox protein Hox-2C; Homeobox protein Hox-B7; Hox 2.3; Hox 2.3, mouse, homolog of; Hox-2.3; HOX2; HOX2C; Hoxb7; HXB7_HUMAN.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 细胞生物 转录调节因子 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Horse, Sheep,
- 产品应用
- WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 24kDa
- 细胞定位
- 细胞核
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human HOXB7:101-200/217
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
The Hox proteins play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. The mammalian HOX gene complex consists of 39 genes that are located on four linkage groups, which are dispersed over four chromosomes. A segment of the HoxB7 proximal promoter drives renal expression of reporter genes specifically in the ureteric bud and collecting ducts. Expression levels of HoxB7 are lower in lymph node metastasis-positive cancer tissues than negative cancer tissues. These results suggest that aberrant expression of HOX genes is related to the development of breast cancer and malignant behavior of cancer cells.
Function:
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Subcellular Location:
Nucleus.
Similarity:
Belongs to the Antp homeobox family.
Contains 1 homeobox DNA-binding domain.
SWISS:
P09629
Gene ID:
3217
Database links:Entrez Gene: 3217Human
Entrez Gene: 15415Mouse
Entrez Gene: 497985Rat
Omim: 142962Human
SwissProt: Q9TT89Cow
SwissProt: P09629Human
SwissProt: P09024Mouse
SwissProt: P18864Rat
Unigene: 436181Human
Unigene: 390366Mouse
Unigene: 113631Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.