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货号： bs-17190R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-17190R
- 英文名称
- IWS1
- 中文名称
- IWS1蛋白抗体
- 别 名
- DKFZp761G0123; FLJ10006; FLJ14655; FLJ32319; Interacts with Spt6; iws1; IWS1 homolog; IWS1-like protein; IWS1_HUMAN; IWS1L; MGC126375; MGC126376; OTTHUMP00000162262; Protein IWS1 homolog.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 细胞生物 免疫学 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 92kDa
- 细胞定位
- 细胞核
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human IWS1:601-700/819
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.
- PubMed
- PubMed
- 产品介绍
- background:
HIws1 is an 819 amino acid nuclear protein that contains one TFIIS N-terminal domain. Belonging to the IWS1 family, hIws1 exists as three alternatively spliced isoforms, which are encoded by a gene mapping to human chromosome 2q14.3. Chromosome 2 is the second largest human chromosome, consisting of 237 million bases, encoding over 1,400 genes and making up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr鰉 syndrome, is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes
Subunit:
Interacts with SUPT6H; binds preferentially to the POLR2A-bound SUPT6H. Interacts with ALYREF/THOC4, SETD2 and PRMT5. Interacts with HDGFRP2.
Subcellular Location:
Nucleus.
Similarity:
Belongs to the IWS1 family.
Contains 1 TFIIS N-terminal domain.
SWISS:
Q96ST2
Gene ID:
55677
Database links:Entrez Gene: 55677Human
Entrez Gene: 73473Mouse
Entrez Gene: 291705Rat
SwissProt: Q96ST2Human
SwissProt: Q8C1D8Mouse
SwissProt: Q3SWT4Rat
Unigene: 469879Human
Unigene: 66853Mouse
Unigene: 206133Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.