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货号: bs-17116R 基本售价: 1380.0 元 规格: 100ul
- 规格:100ul
- 价格:1380.00元
- 规格:200ul
- 价格:2200.00元
产品信息
- 产品编号
- bs-17116R
- 英文名称
- RNF109/TRIM56
- 中文名称
- 环指蛋白109抗体
- 别 名
- A130009K11Rik; DKFZp667O116; E3 ubiquitin-protein ligase TRIM56; FLJ35608; Gm452; MGC37358; OTTMUSP00000027392; RING finger protein 109; RNF109; TRI56_HUMAN; Trim56; Tripartite motif containing protein 56; Tripartite motif-containing protein 56.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 细胞生物 转录调节因子 表观遗传学 环指蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 81kDa
- 细胞定位
- 分泌型蛋白
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human RNF109/TRIM56:651-755/755
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
E3 ubiquitin-protein ligase that mediates Lys-63-linked polyubiquitination of TMEM173/STING, thereby playing a key role in innate immunity. TMEM173/STING Lys-63-linked ubiquitination activates the production of type I interferon IFN-beta following detection of pathogen- and host-derived double-stranded DNA.
Function:
E3 ubiquitin-protein ligase that mediates Lys-63-linked polyubiquitination of TMEM173/STING, thereby playing a key role in innate immunity. TMEM173/STING Lys-63-linked ubiquitination activates the production of type I interferon IFN-beta following detection of pathogen- and host-derived double-stranded DNA (By similarity).
Subunit:
Interacts with TMEM173/STING (By similarity).
Subcellular Location:
Cytoplasm.
Similarity:
Belongs to the TRIM/RBCC family.
Contains 2 B box-type zinc fingers.
Contains 1 RING-type zinc finger.
SWISS:
Q9BRZ2
Gene ID:
81844
Database links:Entrez Gene: 81844Human
SwissProt: Q9BRZ2Human
Unigene: 521092Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.