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货号： bs-16956R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-16956R
- 英文名称
- KHDRBS3
- 中文名称
- 信号转导相关蛋白3抗体
- 别 名
- Etle; etoile; KH domain containing RNA binding signal transduction associated 3; KH domain containing RNA binding signal transduction associated protein 3; KH domain-containing; KHDR3_HUMAN; Khdrbs3; RNA binding protein T Star; RNA-binding; RNA-binding protein T-Star; SALP; Sam68 like mammalian protein 2; Sam68 like phosphotyrosine protein; Sam68 like phosphotyrosine protein T STAR; Sam68-like mammalian protein 2; Sam68-like phosphotyrosine protein; signal transduction-associated protein 3; SLM 2; SLM-2; SLM2; T STAR; TSTAR.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 细胞生物 信号转导 转录调节因子 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Cow, Horse, Rabbit,
- 产品应用
- ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 39kDa
- 细胞定位
- 细胞核
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human KHDRBS3:281-346/346
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. May play a role as a negative regulator of cell growth. Inhibits cell proliferation. Involved in splice site selection of vascular endothelial growth factor. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. RNA-binding abilities are down-regulated by tyrosine kinase PTK6. Involved in post-transcriptional regulation of HIV-1 gene expression.
Function:
RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. May play a role as a negative regulator of cell growth. Inhibits cell proliferation. Involved vitro.
Subunit:
Self-associates to form homooligomers.
Subcellular Location:
Nucleus. Localized in a compartment adjacent to the nucleolus, but distinct from the peri-nucleolar one.
Tissue Specificity:
Ubiquitous with higher expression in testis, skeletal muscle and brain. Expressed in the kidney only in podocytes, the glomerular epithelial cells of the kidney. Strongly expressed after meiosis.
Post-translational modifications:
Phosphorylated on tyrosine residues. Isoform 1 C-terminal region is tyrosine-rich, but isoform 2 lacking this C-terminal region is also tyrosine-phosphorylated.
Similarity:
Belongs to the KHDRBS family.
Contains 1 KH domain.
SWISS:
O75525
Gene ID:
10656
Database links:Entrez Gene: 10656Human
Entrez Gene: 13992Mouse
Entrez Gene: 64015Rat
Omim: 610421Human
SwissProt: O75525Human
SwissProt: Q9R226Mouse
SwissProt: Q9JLP1Rat
Unigene: 444558Human
Unigene: 17964Mouse
Unigene: 54682Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.