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货号： bs-16911R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-16911R
- 英文名称
- KCNN2
- 中文名称
- 电导钙激活钾通道蛋白2抗体
- 别 名
- Apamin sensitive small conductance Ca2+ activated potassium; Apamin sensitive small conductance Ca2+ activated potassium channel; hSK2; KCa2.2; Kcnn2; KCNN2_HUMAN; Potassium intermediate/small conductance calcium activated; Potassium intermediate/small conductance calcium activated channel subfamily N member 2; SK2; SKCa 2; SKCa2; Small conductance calcium activated potassium channel; Small conductance calcium activated potassium channel protein 2; Small conductance calcium-activated potassium channel protein 2.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 细胞生物 免疫学 神经生物学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 64kDa
- 细胞定位
- 细胞膜
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human KCNN2:51-113/113
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene is a member of the KCNN family of potassium channel genes. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. Alternate splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]
Function:
Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin.
Subcellular Location:
Membrane.
Tissue Specificity:
Widely expressed.
Similarity:
Belongs to the potassium channel KCNN family. KCa2.2/KCNN2 subfamily.
SWISS:
Q6PJI0
Gene ID:
3781
Database links:Entrez Gene: 3781Human
Entrez Gene: 395579Chicken
Entrez Gene: 404177Cow
Entrez Gene: 474640Dog
Entrez Gene: 140492Mouse
Entrez Gene: 54262Rat
Omim: 605879Human
SwissProt: Q6PJI0Human
SwissProt: Q9H2S1Human
SwissProt: P58390Mouse
SwissProt: Q3UF29Mouse
SwissProt: Q540U9Mouse
SwissProt: Q80X11Mouse
SwissProt: Q8C7F3Mouse
SwissProt: Q8CAD4Mouse
SwissProt: Q8CCH4Mouse
SwissProt: P70604Rat
Unigene: 98280Human
Unigene: 458654Mouse
Unigene: 44421Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.