产品编号bs-0081R
英文名称Caspase-3
中文名称活化半胱胺酸蛋白酶蛋白-3抗体
别    名Caspase-3 subunit p17; APOPAIN; CASP3; Caspase 3 apoptosis related cysteine protease; Caspase3; CPP32; CPP32B; Cysteine protease CPP32; Human cysteine protease CPP32 isoform alpha mRNA complete cds; PARP cleavage protease; SCA 1; SCA1; SREBP cleavage activity 1; Yama; CASP3_HUMAN; Caspase-3; CASP-3; Apopain; Protein Yama; SREBP cleavage activity 1; SCA-1.  
Specific References  (63)     |     bs-0081R has been referenced in 63 publications.
[IF=9.91] Li, Ting, et al. "Proliferation of parenchymal microglia is the main source of microgliosis after ischaemic stroke." Brain (2013): awt287.  Mouse.  
PubMed:24154617
[IF=7.60] Teng, I., et al. "Phospholipid-functionalized mesoporous silica nanocarriers for selective photodynamic therapy of cancer." Biomaterials (2013).  WB ;  Mouse.  
PubMed:23810081
[IF=4.75] Rosenzweig, Derek H., Sing J. Ou, and Thomas M. Quinn. ʺP38 mitogen‐activated protein kinase promotes dedifferentiation of primary articular chondrocytes in monolayer culture.ʺ Journal of Cellular and Molecular Medicine (2013)  WB ;  Bovine.  
[IF=4.26] Rosenzweig, Derek H., et al. "Mechanical injury of bovine cartilage explants induces depth-dependent, transient changes in MAP kinase activity associated with apoptosis." Osteoarthritis and Cartilage (2012).  WB ;  Bovine.  
PubMed:22935788
[IF=4.22] Sondag, Gregory R., et al. "Osteoactivin Induces Transdifferentiation of C2C12 Myoblasts into Osteoblasts." Journal of Cellular Physiology (2013).  Mouse.  
PubMed:24265122
[IF=3.95] Wang, Gang, et al. "Inhibition of hydrogen sulfide synthesis provides protection for severe acute pancreatitis rats via apoptosis pathway." Apoptosis (2013): 1-15.  IHC-P ;  Rat.  
PubMed:23054084
[IF=3.06] Li, Guiying, et al. ʺGremlin Aggravates Hyperglycemia‐Induced Podocyte Injury by a TGFβ/Smad Dependent Signaling Pathway.ʺ Journal of CellularBiochemistry (2013).  WB ;  Mouse.  
[IF=2.61] Lei, Mingxing, et al. ʺGsdma3 is a new factor needed for TNF-α-mediated apoptosis signal pathway in mouse skin keratinocytes.ʺ Histochemistry and cell biology 138.3 (2012): 385-396.  WB, IHC-P ;  Mouse.  
PubMed: 22585037
[IF=2.41] Guan, Junhong, et al. "Bone morphogenetic protein-7 (BMP-7) mediates ischemic preconditioning-induced ischemic tolerance via attenuating apoptosis in rat brain." Biochemical and Biophysical Research Communications (2013).  WB ;  Rat.  
PubMed:24184479
[IF=2.27] Li, M., et al. ʺmiR‐34c works downstream of p53 leading to dairy goat male germline stem‐cell (mGSCs) apoptosis.ʺ Cell Proliferation 46.2 (2013): 223-231.  WB ;  Goat.  
PubMed:23510477
[IF=2.03] Aksu, Ilkay, et al. "Anxiety correlates to decreased blood and prefrontal cortex IGF-1 levels in streptozotocin induced diabetes." Neuroscience Letters (2012).  Rat.  
PubMed:23123774
[IF=1.85] Li, Mingzhao, et al. ʺExpression of miR‐34c in response to overexpression of Boule and Stra8 in dairy goat male germ line stem cells (mGSCs).ʺ Cell Biochemistry and Function (2013).  Goat.  
PubMed:23508548
[IF=5.47] Pan, Bo, et al. "c-Abl Tyrosine Kinase Mediates Neurotoxic Prion Peptide-Induced Neuronal Apoptosis via Regulating Mitochondrial Homeostasis." Molecular Neurobiology (2014): 1-15.  Rat.  
PubMed:24510275
[IF=2.75] Ye, Bengui, et al. "Anti-tumor activity and relative mechanism of ethanolic extract of Marsdenia tenacissima (Asclepiadaceae) against human hematologic neoplasm in vitro and in vivo." Journal of Ethnopharmacology (2014).  WB ;  Human.  
PubMed:24583069
[IF=2.69] Lin, Caiyu, et al. "Lithocarpus Polystachyus Rehd Leaf Aqueous Extract Inhibits Human Breast Cancer Growth In Vitro and In Vivo." Nutrition and Cancer (2014).  WB ;  Human.  
PubMed:24660968
[IF=3.17] Liu, Yang, et al. "Amelioration of Stroke-Induced Neurological Deficiency by Lyophilized Powder of Catapol and Puerarin." International Journal of Biological Sciences 10.4 (2014): 448-456.  WB ;  Mouse.  
PubMed:24719562
[IF=2.52] Yao, Kun, et al. "Knockdown of RLIP76 expression by RNA interference inhibits proliferation, enhances apoptosis, and increases chemosensitivity to daunorubicin in U937 leukemia cells." Tumor Biology (2014): 1-9.  WB ;  Human.  
PubMed:24839008
[IF=2.15] Tang, Xi-Lan, et al. "The Cardioprotective Effect of Protocatechuic Acid on Myocardial Ischemia/Reperfusion Injury." Journal of Pharmacological Sciences 125.2 (2014): 176-183.  WB ;  Rat.  
PubMed:24942213
[IF=2.10] Zhang, Beiru, et al. "The Toxicity Mechanisms of Action of Aβ25–35 in Isolated Rat Cardiac Myocytes." Molecules 19.8 (2014): 12242-12257.  other ;  Rat.  
PubMed:25123188
[IF=3.79] Luo, Xiaoming, et al. "Antimetastasis and antitumor efficacy promoted by sequential release of vascular disrupting and chemotherapeutic agents from electrospun fibers." International Journal of Pharmaceutics (2014).  IHC-P ;  Mouse.  
PubMed:25218185
[IF=2.38] Gao, Hui, et al. "Hispidulin Potentiates the Antitumor Effect of Sunitinib Against Human Renal Cell Carcinoma in Laboratory Models." Cell Biochemistry and Biophysics: 1-8.  WB ;  Human.  
PubMed:25260394
[IF=2.38] Gao, Hui, et al. "shRNA-Mediated EMMPRIN Silencing Inhibits Human Leukemic Monocyte Lymphoma U937 Cell Proliferation and Increases Chemosensitivity to Adriamycin." Cell Biochemistry and Biophysics: 1-9.  WB ;  Human.  
PubMed:25260396
[IF=3.68] Xiao, Ke, et al. "The role of visfatin on the regulation of inflammation and apoptosis in the spleen of LPS-treated rats." Cell and Tissue Research (2014).  IHC-P ;  Rat.  
[IF=3.53] Fang C, Zhang J, Qi D, Fan X, Luo J, et al. (2014) Evodiamine Induces G2/M Arrest and Apoptosis via Mitochondrial and Endoplasmic Reticulum Pathways in H446 and H1688 Human Small-Cell Lung Cancer Cells. PLoS ONE 9(12): e115204.   WB ;  Human.  
PubMed:25506932
[IF=1.14] Wang, J., et al. "Esculetin, a coumarin derivative, exerts in vitro and in vivo antiproliferative activity against hepatocellular carcinoma by initiating a mitochondrial-dependent apoptosis pathway." Brazilian Journal of Medical and Biological Research (2014): 000-000.  WB ;  Mouse.  
PubMed:25517918
[IF=4.20] Tian, A., et al. "Nanoscale TiO 2 nanotubes govern the biological behavior of human glioma and osteosarcoma cells." International Journal of Nanomedicine10 (2015): 2377-2389.  Human.  
PubMed:25848261
[IF=3.84] Kubatka, Peter, et al. "Fruit peel polyphenols demonstrate substantial anti-tumour effects in the model of breast cancer." European Journal of Nutrition(2015): 1-11.  IHC-P ;  Rat.  
PubMed:25930965
[IF=1.55] Jia, Jianping, et al. "A preliminary study of the effect of ECRG4 overexpression on the proliferation and apoptosis of human laryngeal cancer cells and the underlying mechanisms." Molecular Medicine Reports.  Human.  
PubMed:26165988
[IF=2.37] Liu, Jun-Song, et al. "β-elemene enhances the radiosensitivity of gastric cancer cells by inhibiting Pak1 activation." World J Gastroenterol 21.34 (2015): 9945-9956.  WB ;  Human.  
PubMed:26379399
[IF=1.55] Song, Guijun, et al. "Anti-autophagic and anti-apoptotic effects of memantine in a SH-SY5Y cell model of Alzheimers disease via mammalian target of rapamycin-dependent and-independent pathways." Molecular Medicine Reports.  WB ;  Human.  
PubMed:not posted yet
[IF=2.70] Lv, Runxiao, et al. "Neuroprotective effect of allicin in a rat model of acute spinal cord injury." Life Sciences (2015).  WB ;  Rat.  
PubMed:26546416
[IF=2.31] Dong, Liwei, et al. "Echinacoside induces apoptotic cancer cell death by inhibiting the nucleotide pool sanitizing enzyme MTH1." OncoTargets and Therapy 8 (2015): 3649.  Human.  
PubMed:26677335
[IF=0.00] Wang, Yu, et al. "Tanshinone II A Relieves Adriamycin-induced Myocardial Injury in Rat Model." International Journal of Chemistry 8.1 (2016): 40.  WB ;  Rat.  
PubMed:not posted yet
[IF=3.82] Clark, Andrea J., et al. "WO3/Pt nanoparticles are NADPH oxidase biomimetics that mimic effector cells in vitro and in vivo." Nanotechnology27.6 (2015): 065101.  
PubMed:26683660
[IF=3.47] Kubatka, Peter, et al. "Oregano demonstrates distinct tumour-suppressive effects in the breast carcinoma model." European Journal of Nutrition (2016): 1-14.  IHC-P ;  Rat.  
PubMed:26907089
[IF=1.06] Zhang, Xiaolin, and Hao Yu. "Matrine inhibits diethylnitrosamine-induced HCC proliferation in rats through inducing apoptosis via p53, Bax-dependent caspase-3 activation pathway and down-regulating MLCK overexpression (Supplement 2016)." Iranian Journal of Pharmaceutical Research (2016).  WB ;  Rat.  
PubMed:27642320
[IF=3.40] Gao, Hui, et al. "Hispidulin induces mitochondrial apoptosis in acute myeloid leukemia cells by targeting extracellular matrix metalloproteinase inducer."American Journal of Translational Research 8.2 (2016): 1115-1132  WB ;  Human.  
PubMed:27158398
[IF=2.53] Yoshinaga, Ayana, et al. "NEU3 inhibitory effect of naringin suppresses cancer cell growth by attenuation of EGFR signaling through GM3 ganglioside accumulation." European Journal of Pharmacology (2016).  WB ;  Human.  
PubMed:27105818
[IF=0.00] Petty, Howard R. "NANOPARTICLE THERAPY IN CANCER." U.S. Patent No. 20,150,335,744. 26 Nov. 2015.  IF(ICC) ;  
PubMed:1111
[IF=2.90] Shan, Ming, and Ting-Jun Fan. "Cytotoxicity of carteolol to human corneal epithelial cells by inducing apoptosis via triggering the Bcl-2 family protein-mediated mitochondrial pro-apoptotic pathway." Toxicology in Vitro (2016).  ELISA ;  Human.  
PubMed:27216471
[IF=2.10] Hu, Hanhua, et al. "Drug-induced apoptosis of Echinococcus granulosus protoscoleces." Parasitology research 109.2 (2011): 453-459.  IHC-P ;  Others.  
PubMed:21365454
[IF=1.51] Sun, Y‐L., et al. "Relationship between apoptosis and proliferation in granulosa and theca cells of cystic follicles in sows." Reproduction in domestic animals 47.4 (2012): 601-608.  IHC-P ;  Pig.  
PubMed:22023076
[IF=1.55] Ding, Qing, et al. "8‑bromo‑7‑methoxychrysin induces apoptosis by regulating Akt/FOXO3a pathway in cisplatin‑sensitive and resistant ovarian cancer cells." Molecular medicine reports 12.4 (2015): 5100-5108.  WB ;  Human.  
PubMed:26151347
[IF=4.38] Ma, Xiangyi, et al. "DT390-triTMTP1, a novel fusion protein of diphtheria toxin with tandem repeat TMTP1 peptide, preferentially targets metastatic tumors." Molecular pharmaceutics 10.1 (2013): 115-126.  IHC-P ;  Human.  
PubMed:23198829
[IF=1.55] Han, Ning, et al. "Agmatine protects Müller cells from high‑concentration glucose‑induced cell damage via N‑methyl‑D‑aspartic acid receptor inhibition." Molecular medicine reports 12.1 (2015): 1098-1106.  WB ;  Rat.  
PubMed:25816073
[IF=2.86] Liu, Yaping, et al. "Overexpression of PRL7D1 in Leydig Cells Causes Male Reproductive Dysfunction in Mice." International Journal of Molecular Sciences 17.1 (2016): 96.  WB ;  Mouse.  
PubMed:26771609
[IF=1.83] KASSAYOVÁ, MONIKA, et al. "Anticancer and Immunomodulatory Effects of Lactobacillus plantarum LS/07, Inulin and Melatonin in NMU-induced Rat Model of Breast Cancer." Anticancer Research 36.6 (2016): 2719-2728.  IHC-P ;  Rat.  
PubMed:27272781
[IF=1.72] Zhao, Jun, et al. "The cytotoxic and pro-apoptotic effects of phenylephrine on corneal stromal cells via a mitochondrion-dependent pathway both in vitro and in vivo." Experimental and Toxicologic Pathology (2016).  ELISA ;  Human.  
PubMed:27344612
[IF=6.01] Chen, Zhoujiang, et al. "Tunable conjugation densities of camptothecin on hyaluronic acid for tumor targeting and reduction-triggered release." Acta Biomaterialia (2016).  IHC-P ;  Mouse.  
PubMed:27424081
[IF=3.92] Wei, Gang, et al. "β-Asarone inhibits neuronal apoptosis via the CaMKII/CREB/Bcl-2 signaling pathway in an in vitro model and AβPP/PS1 mice." Journal of Alzheimers Disease 33.3 (2013): 863-880.  IF(ICC) ;  Mouse.  
PubMed:23064259
[IF=1.48] Liu, Yong‑Chao, et al. "RNAi-mediated gene silencing of vascular endothelial growth factor C suppresses growth and induces apoptosis in mouse breast cancer in vitro and in vivo." Oncology Letters. (2016)  WB ;  Mouse.  
PubMed:27666771
[IF=2.13] Cetintas, Vildan Bozok, et al. "Effects of flavopiridol on critical regulation pathways of CD133high/CD44high lung cancer stem cells." Medicine 95.43 (2016): e5150.  IF(ICC) ;  Mouse.  
PubMed:27787370
[IF=3.85] Wang, Yandi, et al. "Regulation of steroid hormones and energy status with cysteamine and its effect on spermatogenesis." Toxicology and Applied Pharmacology (2016).  IHC-P ;  Sheep.  
PubMed:27815134
[IF=5.23] Zhao, Yong, et al. "Hydrogen Sulfide and/or Ammonia Reduces Spermatozoa Motility through AMPK/AKT Related Pathways." Scientific Reports 6 (2016): 37884.  WB ;  Pig.  
PubMed:27883089
[IF=1.64] Kosutova, P., et al. "Intravenous dexamethasone attenuated inflammation and influenced apoptosis of lung cells in an experimental model of acute lung injury." Physiological research 65.Supplementum 5 (2016): S663.  IHC-P ;  Rabbit.  
PubMed:28006948
[IF=2.38] Abdel-Hamid, Nagwa I., Mona F. El-Azab, and Yasser M. Moustafa. "Macrolide antibiotics differentially influence human HepG2 cytotoxicity and modulate intrinsic/extrinsic apoptotic pathways in rat hepatocellular carcinoma model." Naunyn-Schmiedebergs Archives of Pharmacology (2017): 1-17.  IHC-P ;  Rat.  
PubMed:28070612
[IF=1.55] Yang, Jinjiang, Ying Lu, and Ai Guo. "Platelet-rich plasma protects rat chondrocytes from interleukin-1β-induced apoptosis." Molecular Medicine Reports 14.5 (2016): 4075-4082.  WB ;  Rat.  
PubMed:27665780
[IF=0.87] Ochigbo, Grace Onyeche, et al. "Polyphenol-rich fraction of Parquetina nigrescens mitigates dichlorvos-induced neurotoxicity and apoptosis." Journal of Ayurveda and Integrative Medicine (2017).  Rat.  
PubMed:28256303
[IF=1.56] Qu, Zhongyuan, et al. "Chelidonine induces mitotic slippage and apoptotic-like death in SGC-7901 human gastric carcinoma cells." Molecular medicine reports 13.2 (2016): 1336-1344.  WB ;  Human.  
PubMed:26677104
[IF=2.33] Yang, Juan, Guiyuan Li, and Keqiang Zhang. "Pro-survival effects by NF-κB, Akt and ERK (1/2) and anti-apoptosis actions by Six1 disrupt apoptotic functions of TRAIL-Dr4/5 pathway in ovarian cancer." Biomedicine & Pharmacotherapy 84 (2016): 1078-1087.  WB ;  Human.  
PubMed:27780136
[IF=3.23] Wang, Yu, et al. "Ibutilide treatment protects against ER stress induced apoptosis by regulating calumenin expression in tunicamycin treated cardiomyocytes." PloS one 12.4 (2017): e0173469.  WB ;  Rat.  
PubMed:28399139
[IF=4.94] Kubatka, Peter, et al. "Antineoplastic effects of clove buds (Syzygium aromaticum L.) in the model of breast carcinoma." Journal of Cellular and Molecular Medicine (2017).  IHC-P ;  Rat.  
PubMed:28524540
[IF=3.13] Zhang, Wen-feng, et al. "Angelica polysaccharides inhibit the growth and promote the apoptosis of U251 glioma cells in vitro and in vivo." Phytomedicine (2017).  WB ;  Human.  
PubMed:0
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