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货号： bs-16627R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-16627R
- 英文名称
- IMPG2
- 中文名称
- IMPG2蛋白抗体
- 别 名
- Interphotoreceptor matrix proteoglycan 2; Interphotoreceptor matrix proteoglycan 200; Interphotoreceptor matrix proteoglycan of 200 kDa; IPM 200; IPM200; IMPG2_HUMAN; Sialoprotein associated with cones and rods proteoglycan; SPACRCAN.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 细胞生物 免疫学 神经生物学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Cow, Rabbit, Sheep,
- 产品应用
- ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 136kDa
- 细胞定位
- 细胞膜
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human IMPG2:951-1050/1241 <Extracellular>
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
The protein encoded by this gene binds chondroitin sulfate and hyaluronan and is a proteoglycan. The encoded protein plays a role in the organization of the interphotoreceptor matrix and may promote the growth and maintenance of the light-sensitive photoreceptor outer segment. Defects in this gene are a cause of retinitis pigmentosa type 56 and maculopathy, IMPG2-related.[provided by RefSeq, Mar 2011]
Function:
IMPG2 (Interphotoreceptor matrix proteoglycan 2) is part of an extracellular complex occupying the interface between photoreceptors and the retinal pigment epithelium in the fundus of the eye. IMPG2 is part of an extracellular complex occupying the interface between photoreceptors and the retinal pigment epithelium in the fundus of the eye.
Subcellular Location:
Membrane; Single pass type I membrane protein
Tissue Specificity:
Expressed in the retina. Expressed by photoreceptors of the interphotoreceptor matrix (IPM) surrounding both rods and cones. IPM occupies the subretinal space between the apices of the retinal pigment epithelium and the neural retina. Detected in the pineal gland.
Post-translational modifications:
Highly glycosylated (N- and O-linked carbohydrates).
DISEASE:
Retinitis pigmentosa 56 (RP56) [MIM:613581]: A retinal dystrophy belonging to the group of pigmentary retinopathies. Retinitis pigmentosa is characterized by retinal pigment deposits visible on fundus examination and primary loss of rod photoreceptor cells followed by secondary loss of cone photoreceptors. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. Note=The disease is caused by mutations affecting the gene represented in this entry.
Maculopathy, IMPG2-related (MACLP-IMPG2) [MIM:613581]: A mild maculopathy characterized by full-field electroretinogram responses within normal limits, normal color vision, elevation of the photoreceptor layer in the foveal region and mild nuclear sclerosis. Note=The disease is caused by mutations affecting the gene represented in this entry.
Similarity:
Contains 2 EGF-like domains.
Contains 2 SEA domains.
SWISS:
Q9BZV3
Gene ID:
50939
Database links:Entrez Gene: 50939Human
Entrez Gene: 224224Mouse
Entrez Gene: 245919Rat
Omim: 607056Human
SwissProt: Q9BZV3Human
SwissProt: Q80XH2Mouse
SwissProt: P70628Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.