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货号： bs-16571R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-16571R
- 英文名称
- Transglutaminase 5
- 中文名称
- 谷氨酰胺转胺酶5抗体
- 别 名
- Protein glutamine gamma glutamyltransferase 5; Protein-glutamine gamma-glutamyltransferase 5; TG(X); TGase 5; TGase X; TGase-5; TGase5; TGM5; TGM5_HUMAN; TGMX; TGX; Transglutaminase X; Transglutaminase-5.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 细胞生物 信号转导 结合蛋白 新陈代谢
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 81kDa
- 细胞定位
- 细胞膜
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Transglutaminase 5:551-650/720
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
This gene encodes a member of the transglutaminase family. The encoded protein catalyzes formation of protein cross-links between glutamine and lysine residues, often resulting in stabilization of protein assemblies. This reaction is calcium dependent. Mutations in this gene have been associated with acral peeling skin syndrome. [provided by RefSeq, Oct 2009]
Function:
Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Contributes to the formation of the cornified cell envelope of keratinocytes.
Subcellular Location:
Cytoplasm. Associated with intermediate filaments.
Tissue Specificity:
Expressed in foreskin keratinocytes.
DISEASE:
Defects in TGM5 are a cause of peeling skin syndrome type A (APSS) [MIM:609796]. A non-inflammatory form of peeling skin syndrome, a genodermatosis characterized by the continuous shedding of the outer layers of the epidermis. In APSS patients, skin peeling is strictly limited to the dorsa of the hands and feet, and it is accompanied by accompanied by painless erythema and spontaneous non-scarring healing. Ultrastructural and histological analysis shows a level of blistering high in the epidermis at the stratum granulosum-stratum corneum junction.
Similarity:
Belongs to the transglutaminase superfamily. Transglutaminase family.
SWISS:
O43548
Gene ID:
9333
Database links:Entrez Gene: 9333Human
Entrez Gene: 74176Mouse
Entrez Gene: 691929Rat
Omim: 603805Human
SwissProt: O43548Human
SwissProt: Q3V1F9Mouse
SwissProt: Q9D7I9Mouse
Unigene: 129719Human
Unigene: 20187Mouse
Unigene: 198646Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.